Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

186 questions · 190 findings · 17 reviews · Haematology

No studies found 47 · 24.7%GRADE not reported 21 · 11.1%Very low 26 · 13.7%Low 47 · 24.7%Moderate 37 · 19.5%High 12 · 6.3%

Fewer vs more courses of chemotherapy (with or without radiotherapy

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (early stages)

Fewer showed no clear difference in secondary malignant neoplasms compared with more courses of chemotherapy (with or without radiotherapy (moderate certainty).

1 finding from 1 review

Fewer vs more courses of chemotherapy (with or without radiotherapy

Death · Patients with untreated Hodgkin lymphoma (early stages)

Fewer showed no clear difference in death compared with more courses of chemotherapy (with or without radiotherapy (high certainty).

1 finding from 1 review

Fewer vs more courses of chemotherapy (with or without radiotherapy

Progression/relapse · Patients with untreated Hodgkin lymphoma (early stages)

Fewer showed no clear difference in progression/relapse compared with more courses of chemotherapy (with or without radiotherapy (high certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one severe/life‐threatening bleeding episode · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one severe/life‐threatening… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours with thrombocytopenia during chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review