Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

47 questions · 47 findings · 6 reviews · Colorectal

No studies found 2 · 4.3%GRADE not reported 0 · 0%Very low 13 · 27.7%Low 10 · 21.3%Moderate 13 · 27.7%High 9 · 19.1%

Adjunctive Coriolus versicolor vs no adjunctive treatment

Diarrhoea · adults (aged 18+) with colorectal cancer

It is very uncertain whether adjunctive Coriolus versicolor changes adverse events: Diarrhoea ‐ compared with no adjunctive treatment (very low certainty).

1 finding from 1 review

Adjunctive Coriolus versicolor vs no adjunctive treatment

Adverse events: Neutrophils decreased ‐ · adults (aged 18+) with colorectal cancer

It is very uncertain whether adjunctive Coriolus versicolor changes adverse events: Neutrophils decreased ‐ compared with no adjunctive treatment (very low certainty).

1 finding from 1 review

Adjunctive Coriolus versicolor vs no adjunctive treatment

Adverse effect: fatigue · adults (aged 18+) with colorectal cancer

It is very uncertain whether adjunctive Coriolus versicolor changes adverse events: Fatigue ‐ compared with no adjunctive treatment (very low certainty).

1 finding from 1 review

IRI with fluoropyrimidines vs single agent IRI

Progression‐free survival (PSF) · patients with advanced and/or metastatic colorectal cancer

IRI with fluoropyrimidines probably leads to lower progression‐free survival (Disease progression) compared with single agent IRI (moderate certainty).

1 finding from 1 review