Cardiovascular events · patients with hypertension
First‐line thiazides probably leads to lower total cardiovascular events Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
Stroke · patients with hypertension
First‐line thiazides showed no clear difference in total stroke Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
Total CHD Duration: 1 to 5 years · patients with hypertension
First‐line thiazides showed no clear difference in total CHD Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
Congestive heart failure · patients with hypertension
First‐line thiazides probably leads to lower total congestive heart failure Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
Adverse effects (side effects; treatment withdrawals) · patients with hypertension
First‐line thiazides may leads to lower withdrawals due to adverse effects Duration: 1 to 5 years compared with first‐line calcium channel blockers (low certainty).
1 finding from 1 review
Total mortality Duration: 1 to 5 years · patients with hypertension
First‐line thiazides showed no clear difference in total mortality Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
Total serious adverse events Duration: 1.75 to 3 years · patients with hypertension
First‐line thiazides showed no clear difference in total serious adverse events Duration: 1.75 to 3 years compared with first‐line calcium channel blockers (low certainty).
1 finding from 1 review
Kidney failure · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hyperkalaemia · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular events · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Doubling serum creatinine · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
AKI · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proteinuria · proteinuric CKD
1 finding from 1 review
eGFR · proteinuric CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · kidney transplant recipients
ACE Inhibitors showed no clear difference in death compared with calcium channel blockers (low certainty).
1 finding from 1 review
Graft loss · kidney transplant recipients
ACE Inhibitors showed no clear difference in graft loss compared with calcium channel blockers (low certainty).
1 finding from 1 review
GFR · kidney transplant recipients
1 finding from 1 review
Acute rejection · kidney transplant recipients
It is very uncertain whether ACE Inhibitors changes acute rejection compared with calcium channel blockers (very low certainty).
1 finding from 1 review
Proteinuria · kidney transplant recipients
1 finding from 1 review