Participant assessment of success by analysing scores and scales ‐ 4 weeks · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in participant assessment success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).
1 finding from 1 review
Major adverse events (eyelid ptosis, eyelid sensory disorder, strabismus) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in major adverse events ‐ Any major adverse events (eyelid ptosis,… compared with onabotulinumtoxinA 20U (moderate certainty).
1 finding from 1 review
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in physician assessment of success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).
1 finding from 1 review
Total adverse events · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in total adverse events compared with onabotulinumtoxinA 20U (moderate certainty).
1 finding from 1 review
Duration of treatment effect ‐ not measured · glabellar lines
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant global assessment of success Not measured · glabellar lines
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Major adverse events · glabellar lines
It is very uncertain whether summary of Findings Table ‐ IncobotulinumtoxinA 24U changes major adverse events compared with onabotulinumtoxinA 24U (very low certainty).
1 finding from 1 review
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ IncobotulinumtoxinA 24U showed no clear difference in physician assessment of success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 24U (low certainty).
1 finding from 1 review
Total adverse events · glabellar lines
It is very uncertain whether summary of Findings Table ‐ IncobotulinumtoxinA 24U changes total adverse events compared with onabotulinumtoxinA 24U (very low certainty).
1 finding from 1 review
Duration of treatment effect ‐ not measured · glabellar lines
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall cervical dystonia improvement as · adults with cervical dystonia
1 finding from 1 review
Withdrawals due to adverse events · adults with cervical dystonia
Botulinum neurotoxin B showed no clear difference in proportion of withdrawals due to adverse events compared with placebo (low certainty).
1 finding from 1 review
Cervical dystonia‐specific pain · adults with cervical dystonia
1 finding from 1 review
Subjective change as assessed by the patient at week 4 · adults with cervical dystonia
1 finding from 1 review
Proportion of participants with adverse events · adults with cervical dystonia
It is very uncertain whether botulinum neurotoxin B changes proportion of participants with adverse events compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects: dry mouth · adults with cervical dystonia
Botulinum neurotoxin B leads to higher adverse events: dry mouth compared with placebo (high certainty).
1 finding from 1 review
Dysphagia · adults with cervical dystonia
Botulinum neurotoxin B leads to higher adverse events: dysphagia compared with placebo (high certainty).
1 finding from 1 review
Partcipant assessment of success · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher partcipant assessment of success compared with placebo (moderate certainty).
1 finding from 1 review
Duration of treatment effect · glabellar lines
1 finding from 1 review
Major adverse events · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher major adverse events compared with placebo (moderate certainty).
1 finding from 1 review