Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Caries increment, surface index D(M)FS · Children (permanent teeth; baseline 8 to 10 years)
1 finding from 1 review
Caries increment, surface index D(M)FS · Infants/young children (primary teeth; baseline about 1 to 3 years)
1 finding from 1 review
Number of children with a caries increment · Children (permanent teeth; baseline 8 to 10 years)
Xylitol lozenges (4.7 g/day) showed no clear difference in number of children with a caries increment compared with no treatment; GRADE not reported.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in deciduous (primary) teeth/surfaces (dmf index) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
2 findings from 1 review
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
3 findings from 1 review
Caries increment on permanent tooth surfaces (DMFS, approximal surfaces) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in deciduous (primary) teeth/surfaces (dmf index) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries in deciduous teeth (change in dmft) · Children and adolescents aged 16 years or less
1 finding from 1 review
Oral disease outcomes, including dental caries estimates · People of all ages and abilities served through primary care and related settings (children, pregnant women, older adults in…
Most studies reported improved oral disease outcomes with integration strategies (8 of 9 studies improved, 1 no change; 9 studies, narrative synthesis; ungraded).
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · Patients with drooling (sialorrhea) due to neurological disease
In one RCT, BoNT-B 2500 U was not associated with a statistically significant increase in new caries versus placebo (RR 2.4, 95% CI 0.48 to 11.80; not significant).
2 findings from 1 review
Projected Significant Caries (SiC) index · Alaska Native children (below age 18)
A simulation projected a 50% drop in the Significant Caries index for children (12.3 to 6.1) under the PDHA model (certainty not graded).
2 findings from 1 review
Projected proportion of caries-free children (5-18 years) · Alaska Native children (below age 18)
A simulation projected 0% of children aged 5-18 would be caries-free under the baseline scenario (certainty not graded).
3 findings from 1 review
Dental caries: prevalence of root caries · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…
Triclosan/copolymer-containing fluoride toothpaste probably leads to lower root caries at 36 months (Katz Root Caries Index) compared with fluoride toothpaste without triclosan (moderate certainty).
1 finding from 1 review
Coronal caries increment · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…
Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in coronal caries increment at 30 to 36 months (decayed filled teeth,… compared with fluoride toothpaste without triclosan (high certainty).
2 findings from 1 review
Significant caries index · Alaska children
The PDHA program was projected to reduce the SiC index 50% from 12.3 to 6.1 for children, without a GRADE rating.
1 finding from 1 review
Significant caries index · Alaska children aged 12 years
The PDHA program was projected to reduce the SiC index 70% from 10.5 to 3.3 for 12-year-olds, without a GRADE rating.
1 finding from 1 review
Change in Mutans streptococci (MS) and Lactobacilli in saliva · Schoolchildren (6-9 years), high caries risk
The single stevia trial (Cocco 2019) reported a significant reduction in salivary Mutans streptococci and lactobacilli, but gave no effect size and was not GRADE-rated.
1 finding from 1 review
Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis. 2024 All outcomes42 days · Schoolchildren in Italy, high caries risk; sweetener delivered as a daily snack · Single study (Cocco 2019); not pooled
Cocco 2019 (the only high-intensity sweetener trial): the stevia snack showed a significant decrease in MS (P < .01) and in lactobacilli (P = .03) versus baseline, whereas the white-sugar snack showed no significant…
1 study · 271 participants
GRADE not reported