Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

135 questions · 141 findings · 17 reviews · Skin

No studies found 17 · 12.1%GRADE not reported 14 · 9.9%Very low 14 · 9.9%Low 54 · 38.3%Moderate 30 · 21.3%High 12 · 8.5%

ALA‐PDT vs blue light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

ALA‐PDT showed no clear difference in investigator's global assessment (IGA) of improvement Treatment… compared with blue light only (low certainty).

1 finding from 1 review

MAL‐PDT vs red light only

Paticipant's global assessment of improvement ‐ Not measured · Moderate and severe acne vulgaris

The review found no eligible studies for this question.

1 finding from 1 review
  • Light therapies for acne 2016 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Specific allergen immunotherapy vs no immunotherapy

Investigator‐ or physician‐rated global assessment of disease severity · adults and children with atopic eczema and inhalant allergen sensitisation

It is very uncertain whether specific allergen immunotherapy changes investigator‐ or physician‐rated global assessment of disease severity compared with no immunotherapy (very low certainty).

1 finding from 1 review

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in physician‐assessed improvement in rosacea severity Investigator's… compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review

Low dose isotretinoin 0.3 mg/kg vs doxycycline

Assessment of erythema or telangiectasia Improved or healed · Participants with rosacea

Low dose isotretinoin 0.3 mg/kg showed no clear difference in assessment of erythema or telangiectasia Improved or healed compared with doxycycline 50‐100 mg (high certainty).

1 finding from 1 review

Topical ivermectin vs placebo

Assessment of erythema or telangiectasia ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Topical brimonidine vs vehicle

Participant‐assessed improvement in rosacea severity Patient Satisfaction Assessment ‐ grade 2 improvement · Participants with rosacea
1 finding from 1 review