What do systematic reviews say?

Antibiotics vs placebo or no treatment

Any antibiotics showed no clear difference in maternal adverse reactions № of participants: 2593 (1 RCT) compared with placebo or no treatment (low certainty).

• Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
  RR 2 [0.18, 22.05]
  Studies not reported
  Low

Topical antibiotics vs another topical antibiotic or placebo

• Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Low molecular weight heparin vs active control

Low‐molecular‐weight heparin showed no clear difference in any VTE compared with with active control (1); GRADE not reported.

• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  RR 4.81 [0.24, 95.58]
  Studies not reported
  GRADE not reported
• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ultra‐low‐molecular‐weight heparin vs placebo

Ultra‐low‐molecular‐weight heparin leads to lower any VTE compared with placebo (high certainty).

• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  RR 0.36 [0.22, 0.6]
  1 study · 3212 participants
  High

DOAC vs placebo

DOAC probably leads to lower any VTE compared with placebo (moderate certainty).

• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  RR 0.55 [0.34, 0.9]
  2 studies · 1404 participants
  Moderate

Vitamin K antagonists vs active control

The review found no eligible studies for this question.

• Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  282 studies · 50812 participants
  GRADE not reported

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  41 studies · 6156 participants
  Moderate

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 participants
  GRADE not reported

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 120 participants
  Low

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

The review found no eligible studies for this question.

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1678 participants
  Low

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

The review found no eligible studies for this question.

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 327 participants
  Low

Intervention not reported

• Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Very low