Findings

What do systematic reviews say?

173 questions · 259 findings · 5 reviews · Periodontology

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No studies found 62 · 23.9%GRADE not reported 137 · 52.9%Very low 52 · 20.1%Low 5 · 1.9%Moderate 3 · 1.2%High 0 · 0%

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Gestational age (preterm birth < 37 weeks) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes gestational age (preterm birth < 37 weeks) compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

3 findings from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
SRP + antimicrobial vs alternative mechanical treatment + placebo
RR 1.40 [0.67, 2.92]
1 study · 243 participants
Very low
Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
SRP vs alternative mechanical treatment
RR 0.87 [0.46, 1.67]
4 studies · 1168 participants
Very low
Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
SRP + antimicrobial vs SRP + placebo
RR 3.08 [1.15, 8.20]
1 study · 243 participants
Very low

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Pre‐eclampsia · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Pre-eclampsia: Not reported for this comparison.
0 studies
No studies found

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 1.06 [0.60, 1.85]
2 studies · 855 participants
Very low

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Low birth weight < 1500 g · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes low birth weight < 1500 g compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 1.85 [0.69, 4.96]
1 study · 756 participants
Very low

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Percentage of bleeding on probing (BOP) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower bleeding on probing compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
MD -28.00 [-38.54, -17.46]
1 study · 53 participants
GRADE not reported

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Maternal death · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Maternal mortality: Not reported for this comparison.
0 studies
No studies found

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Gingival index (GI) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… showed no clear difference in gingival index compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
MD -28.00 [-144.13, 88.13]
1 study · 53 participants
GRADE not reported

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Adverse effects of therapy · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Adverse effects of therapy: Not reported for this comparison.
0 studies
No studies found

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Preterm birth < 35 weeks · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Preterm births < 35 weeks reported in four studies across three subcomparisons; none of the subcomparisons showed a difference; SRP versus alternative mechanical treatment not pooled due to considerable heterogeneity;…
4 studies
Very low

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Probing pocket depth · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, alone or with… led to lower probing depth compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
MD -0.93 [-1.12, -0.74]
1 study · 53 participants
GRADE not reported

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Small‐for‐gestational age · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

The review found no eligible studies for this question.

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Small for gestational age: Not reported for this comparison.
0 studies
No studies found

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Gingival index (GI) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower gingival index (GI) compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
SMD -1.75 [-2.27, -1.24]
12 studies
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

HbA1c (glycated haemoglobin), change · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… probably leads to lower hbA1c (glycated haemoglobin), change compared with no active intervention/usual care (moderate certainty).

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
MD -0.43 [-0.59, -0.28]
30 studies · 2443 participants
Moderate

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Quality of life indicators · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
Three studies measured QoL. Vergnes 2018: overall GOHAI adjusted MD 7.0 (95% CI 2.4 to 11.6), 79 participants (better oral health-related QoL); no clear change in general SF-36 QoL. D'Aiuto 2018 ADDQoL better in…
3 studies
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Plaque index (PI) / oral hygiene · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower plaque index (PI) / oral hygiene compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
SMD -2.05 [-2.57, -1.53]
18 studies
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Probing pocket depth (PPD/PD) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower probing pocket depth (PPD/PD) compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
MD -0.56 [-0.72, -0.40]
21 studies
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Percentage of bleeding on probing (BOP) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

Periodontal treatment (subgingival instrumentation, with or without… led to lower bleeding on probing (BOP) compared with no active intervention/usual care; GRADE not reported.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
MD -15.56 [-21.77, -9.36]
14 studies
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
Included studies did not report data on diabetic complications (some reported medication changes only)
0 studies
No studies found

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Adverse effects of treatment · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
SoF comment: insufficient evidence to determine whether SRP for glycaemic control is associated with any harms; most studies did not evaluate adverse effects. Where reported (e.g. D'Aiuto 2018) serious adverse events…
Studies not reported
GRADE not reported

Periodontal treatment (subgingival instrumentation, with or without antimicrobials/surgery) vs usual care or no treatment

Resource implications (e.g. cost of incontinence management methods) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of periodontitis for glycaemic control in people with diabetes mellitus 2022 · Cochrane All outcomes
3-4 months
Included studies did not report cost data. A brief economic commentary drew on four external economic evaluations (Smits 2020, Nasseh 2017, Choi 2020, Soloweij-Wedderburn 2017) suggesting potential cost…
0 studies
No studies found