Findings

What do systematic reviews say?

48 questions · 48 findings · 7 reviews · Pregnancy and Childbirth

No studies found 3 · 6.3%GRADE not reported 10 · 20.8%Very low 13 · 27.1%Low 10 · 20.8%Moderate 8 · 16.7%High 4 · 8.3%

Puerperal sepsis/postpartum endometritis · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics probably leads to lower puerperal sepsis/postpartum endometritis compared with placebo (moderate certainty).

1 finding from 1 review

Endometritis · pregnant women undergoing caesarean section

Intravenous route showed no clear difference in endometritis compared with irrigation (lavage) (low certainty).

1 finding from 1 review

Wound infection · pregnant women undergoing caesarean section

It is very uncertain whether intravenous route changes wound infection compared with irrigation (lavage) (very low certainty).

1 finding from 1 review

Routes of administration of antibiotic prophylaxis for preventing infection after caesarean section 2016 · Cochrane Headline outcomes only
RR 0.49 [0.17, 1.43]
7 studies · 859 participants
Very low

Febrile morbidity · pregnant women undergoing caesarean section

It is very uncertain whether intravenous route changes postpartum febrile morbidity compared with irrigation (lavage) (very low certainty).

1 finding from 1 review

Urinary tract infection · pregnant women undergoing caesarean section

It is very uncertain whether intravenous route changes urinary tract infection compared with irrigation (lavage) (very low certainty).

1 finding from 1 review

Routes of administration of antibiotic prophylaxis for preventing infection after caesarean section 2016 · Cochrane Headline outcomes only
RR 0.74 [0.25, 2.15]
5 studies · 660 participants
Very low

Serious infectious complications · pregnant women undergoing caesarean section

1 finding from 1 review

Maternal adverse events · pregnant women undergoing caesarean section

1 finding from 1 review

Routes of administration of antibiotic prophylaxis for preventing infection after caesarean section 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 284 participants
Very low

Infant sepsis (suspected or proven) ‐ not measured · pregnant women undergoing caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Routes of administration of antibiotic prophylaxis for preventing infection after caesarean section 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found