Recurrence of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower recurrence of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Incidence rate of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower incidence rate of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Time to next episode of cellulitis · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis probably leads to lower time to next episode of cellulitis compared with no treatment/placebo (moderate certainty).
1 finding from 1 review
Hospital admissions · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis showed no clear difference in hospitalisation compared with no treatment/placebo (low certainty).
1 finding from 1 review
Adverse reactions to treatment Proportion of participants with adverse reactions to treatment · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis showed no clear difference in any adverse reactions compared with no treatment/placebo (low certainty).
1 finding from 1 review
Quality of life · People with recurrent erysipelas or cellulitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Occurrence of postoperative infection - 4 weeks · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether preoperative antibiotic prophylaxis changes occurrence of postoperative infection - 4 weeks compared with placebo (very low certainty).
1 finding from 1 review
Respiratory tract infections ‐ topical plus systemic prophylaxis versus systemic prophylaxis alone · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in respiratory tract infections ‐ topical plus systemic prophylaxis… compared with no topical prophylaxis (low certainty).
1 finding from 1 review
Respiratory infections · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis may leads to lower respiratory tract infections ‐ topical prophylaxis versus no… compared with no topical prophylaxis (low certainty).
2 findings from 1 review
Overall mortality ‐ topical plus systemic prophylaxis versus systemic prophylaxis alone · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in overall mortality ‐ topical plus systemic prophylaxis versus… compared with no topical prophylaxis (low certainty).
1 finding from 1 review
Overall mortality ‐ topical prophylaxis versus placebo or no treatment · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in overall mortality ‐ topical prophylaxis versus placebo or no treatment compared with no topical prophylaxis (moderate certainty).
1 finding from 1 review
Presence of dry socket · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower dry socket compared with placebo (low certainty).
1 finding from 1 review
Infectious complications · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).
1 finding from 1 review
Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Trismus (dichotomous, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes trismus (dichotomous, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction
The review found no eligible studies for this question.
1 finding from 1 review
Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review