Findings

What do systematic reviews say?

203 questions · 265 findings · 15 reviews

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No studies found 69 · 26%GRADE not reported 116 · 43.8%Very low 50 · 18.9%Low 24 · 9.1%Moderate 6 · 2.3%High 0 · 0%

Summary of findings table ‐ Anger management vs waiting list control

Mental state: psychiatric symptoms measured using the Brief Symptom Inventory (BSI) (Analysis 1.27) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings table ‐ Anger management vs waiting list control

Quality of life ‐ self reported: Comprehensive Quality of Life Scale: Intellectual Disability (COMQoL‐ID: Post‐treatment · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

Summary of findings table ‐ Anger management vs waiting list control

Cost of service utilisation · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
Very low

Summary of findings table ‐ Positive behavioural support vs treatment

Ability to control anger ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Positive behavioural support vs treatment

Adaptive functioning ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT plus standard care vs usual care

Physical aggression · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
Very low

CBT plus standard care vs usual care

Specific behaviour ‐ agitation · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT plus standard care vs usual care

Adverse events: Clinically important effect · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
GRADE not reported

CBT plus standard care vs usual care

Self harm ‐ frequency of self harm · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT plus standard care vs usual care

Mental state: clinically important change in mental state · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT plus standard care vs usual care

Leaving the study early · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 184 participants
Low

CBT plus standard care vs usual care

Quality of life: clinically important change in quality of life · persistent aggressive behaviour or agitation in people with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
6 to 8 months (SoF); similar at 3 to 4 months
MD 0.10 [-0.05, 0.26]
5 studies · 148 participants
Low

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing)

Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with full-mouth disinfection (FMD): scaling/root planing (subgingival… (low certainty).

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
6 to 8 months (SoF); 3 to 4 months favoured FMD
MD -0.05 [-0.23, 0.13]
4 studies · 112 participants
Low

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Pocket closure (sites with PPD <=4 mm) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
Pocket closure (number/proportion of sites with PPD <=4 mm after treatment): 9 studies reported; all showed an increase in closed pockets after treatment; 8 of 9 found no between-group difference; Koshy 2005 found a…
9 studies
GRADE not reported

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Adverse events · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
13 studies provided adverse-event/participant-reported information; 3 reported an event after FMD or FMS; most important harm was increased body temperature. FMD/chlorhexidine-specific harms reported by Fonseca 2015…
13 studies
GRADE not reported

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Adverse events · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
13 studies provided adverse-event/participant-reported information; 3 reported an event after FMD or FMS; most important harm was increased body temperature after treatment. Narrative, not separated by comparison and…
13 studies
GRADE not reported

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Change in probing pocket depth (PPD) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth disinfection (FMD): scaling/root planing (subgingival… showed no clear difference in change in probing pocket depth (PPD) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
6 to 8 months (SoF); similar at 3 to 4 months
MD 0.11 [-0.04, 0.27]
6 studies · 214 participants
Low

Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Change in probing pocket depth (PPD) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in probing pocket depth (PPD) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
6 to 8 months (SoF); similar at 3 to 4 months
MD 0.03 [-0.14, 0.20]
5 studies · 148 participants
Low

Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing) vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart

Tooth loss · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…

The review found no eligible studies for this question.

1 finding from 1 review

Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults 2022 · Cochrane All outcomes
Tooth loss: None of the studies comparing FMD vs control reported tooth loss.
0 studies
No studies found