Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

57 questions · 57 findings · 14 reviews · Headline outcomes only

No studies found 11 · 19.3%GRADE not reported 1 · 1.8%Very low 17 · 29.8%Low 15 · 26.3%Moderate 11 · 19.3%High 2 · 3.5%

Low molecular weight heparin vs unfractionated heparin

Incidence of compromised microcirculation requiring invasive intervention (incision) (analysed by participant/digit, · patients undergoing digital replantation after traumatic amputation

The review found no eligible studies for this question.

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Microvascular insufficiency due to vessel occlusion ‐ arterial occlusion (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes microvascular insufficiency due to vessel occlusion ‐ arterial… compared with unfractionated heparin (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs unfractionated heparin

Microvascular insufficiency due to vessel occlusion ‐ venous occlusion (analysed by participant, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes microvascular insufficiency due to vessel occlusion ‐ venous… compared with unfractionated heparin (very low certainty).

1 finding from 1 review

PAAP vs no PAAP

Rate of exacerbations requiring emergency department treatment or admission · adults with asthma

PAAP showed no clear difference in exacerbation requiring ED or hospitalisation. compared with no PAAP (low certainty).

1 finding from 1 review

PAAP vs no PAAP

Serious adverse events (including mortality) · adults with asthma

It is very uncertain whether PAAP changes serious adverse events (including deaths). compared with no PAAP (very low certainty).

1 finding from 1 review

PAAP vs no PAAP

Rate of exacerbations requiring systemic corticosteroids · adults with asthma

It is very uncertain whether PAAP changes exacerbation requiring OCS. compared with no PAAP (very low certainty).

1 finding from 1 review