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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,112 questions in 171 reviews · Eyes and Vision
current versionsNo studies 587 · 27.8%Ungraded 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nd:YAG laser vs argon‐green laser BCVA: gain of 15 or more ETDRS letters · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.33 [0.02, 7.32] | 1 study · 20 participants | Very low |
0.5 vs 0.1 second exposure Adverse events · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | 1 study · 44 participants | Very low |
Light PRP vs classic PRP BCVA: loss of 15 letters or more ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Light PRP vs classic PRP BCVA: gain of 15 letters or more ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Light PRP vs classic PRP Progression of DR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Light PRP vs classic PRP Regression of PDR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Light PRP vs classic PRP Pain during laser treatment · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.23 [0.03, 1.93] | 1 study · 65 participants | Low |
Light PRP vs classic PRP Adverse events · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | 1 study · 65 participants | Very low |
Mild scatter PRP vs full scatter PRP BCVA: loss of 15 or more ETDRS letters ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Mild scatter PRP vs full scatter PRP BCVA: gain of 15 or more ETDRS letters ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Mild scatter PRP vs full scatter PRP Progression if PDR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Nd:YAG laser vs argon‐green laser Progression of PDR · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 1 [0.07, 14.95] | 1 study · 42 participants | Very low |
Mild scatter PRP vs full scatter PRP Regression of PDR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Mild scatter PRP vs full scatter PRP Pain during laser treatment ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Mild scatter PRP vs full scatter PRP Vision‐related QoL ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Mild scatter PRP vs full scatter PRP Adverse events ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Central PRP vs peripheral PRP BCVA: loss of 15 or more ETDRS letters ‐ 1 year · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 3 [0.67, 13.46] | 1 study · 50 participants | Low |
Central PRP vs peripheral PRP BCVA: gain of 15 or more ETDRS letters ‐ 1 year · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.25 [0.03, 2.08] | 1 study · 50 participants | Low |
Central PRP vs peripheral PRP Progression of DR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Central PRP vs peripheral PRP Regression of PDR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Central PRP vs peripheral PRP Pain during laser treatment ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Central PRP vs peripheral PRP Vision‐related QoL ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Nd:YAG laser vs argon‐green laser Regression of PDR · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 1 [0.87, 1.14] | 1 study · 42 participants | Very low |
Central PRP vs peripheral PRP Adverse events · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | 1 study · 50 participants | Very low |
Centre sparing PRP vs full scatter PRP BCVA: loss of 15 or more ETDRS letters · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.67 [0.3, 1.5] | 1 study · 53 participants | Low |
Centre sparing PRP vs full scatter PRP BCVA: gain of 15 or more ETDRS letters · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Centre sparing PRP vs full scatter PRP Progression of DR ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Centre sparing PRP vs full scatter PRP Regression of PDR · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.96 [0.73, 1.27] | 1 study · 53 participants | Low |
Centre sparing PRP vs full scatter PRP Pain during laser treatment ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Centre sparing PRP vs full scatter PRP Vision‐related QoL ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Centre sparing PRP vs full scatter PRP Adverse events ‐ not reported · proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Extended targeted PRP vs standard PRP BCVA: loss of 15 or more ETDRS letters: · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.94 [0.7, 1.28] | 1 study · 270 participants | Low |
Extended targeted PRP vs standard PRP BCVA: gain of 15 or more ETDRS letters: · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Nd:YAG laser vs argon‐green laser Pain during laser treatment · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 1 [0.36, 2.76] | 2 studies · 62 participants | Very low |
Extended targeted PRP vs standard PRP Progression of DR ‐ not reported · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Extended targeted PRP vs standard PRP Regression of PDR · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 1.11 [0.95, 1.31] | 1 study · 270 participants | Low |
Extended targeted PRP vs standard PRP Pain during laser treatment ‐ not reported · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Extended targeted PRP vs standard PRP Vision‐related QoL ‐ not reported · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Extended targeted PRP vs standard PRP Adverse events · people with diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | Very low |
Nd:YAG laser vs argon‐green laser Vision‐related QoL ‐ not reported · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | no estimate extracted | NR | No studies |
Nd:YAG laser vs argon‐green laser Adverse events · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 1.22 [0.38, 3.94] | 2 studies · 62 participants | Very low |
Diode laser vs argon laser BCVA: loss of 15 or more ETDRS letters · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.95 [0.66, 1.36] | 2 studies · 134 participants | Very low |
Diode laser vs argon laser BCVA: gain of 15 or more ETDRS letters · people with proliferative diabetic retinopathy Different lasers and techniques for proliferative diabetic retinopathy (2018) · Cochrane | RR 0.6 [0.25, 1.45] | 2 studies · 134 participants | Very low |
Vitamin E vs placebo Any AMD · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | RR 0.97 [0.9, 1.06] | 4 studies · 55614 participants | High |
Beta‐carotene vs placebo Neovascular AMD · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | RR 0.61 [0.17, 2.15] | 1 study · 941 participants | Very low |
Beta‐carotene vs placebo Geographic atrophy · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | RR 0.31 [0.03, 2.93] | 1 study · 941 participants | Very low |
Beta‐carotene vs placebo Quality of life · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | no estimate extracted | NR | No studies |
Beta‐carotene vs placebo Adverse effects · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | no estimate extracted | NR | High |
Beta‐carotene vs placebo Resource use and costs · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | no estimate extracted | NR | No studies |
Vitamin C vs placebo Any AMD · general population Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration (2017) · Cochrane | RR 0.96 [0.79, 1.18] | 1 study · 14236 participants | High |