What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes pain score: Acupressure versus no treatment (very low certainty).

• Acupuncture for dysmenorrhoea 2016 · Cochrane Headline outcomes only
  MD 0.96
  2 studies · 140 participants
  Very low

Tibolone vs combined HT

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with combined HT (very low certainty).

• Short‐term and long‐term effects of tibolone in postmenopausal women 2016 · Cochrane Headline outcomes only
  OR 1.69 [0.78, 3.67]
  5 studies · 4835 participants
  Very low

Tibolone vs placebo

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with placebo (very low certainty).

• Short‐term and long‐term effects of tibolone in postmenopausal women 2016 · Cochrane Headline outcomes only
  OR 0.52 [0.21, 1.25]
  4 studies · 5500 participants
  Very low

Intervention not reported

The intervention showed no clear difference in clinical Pregnancy Rate (low certainty).

• Human chorionic gonadotrophin priming for fertility treatment with in vitro maturation 2016 · Cochrane Headline outcomes only
  OR 0.52 [0.26, 1.03]
  2 studies · 282 participants
  Low

Psychological and educational interventions vs usual care or attention control

• Psychological and educational interventions for subfertile men and women 2016 · Cochrane Headline outcomes only
  no estimate extracted
  15 studies · 1464 participants
  Very low

Psychological and educational interventions vs usual care or attention control

• Psychological and educational interventions for subfertile men and women 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 387 participants
  Very low

hCG vs placebo/no treatment

It is very uncertain whether hCG changes live birth or ongoing pregnancy compared with placebo/no treatment (very low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.76 [1.08, 2.86]
  3 studies · 527 participants
  Very low

Progesterone vs progesterone + oestrogen

Progesterone showed no clear difference in live birth or ongoing pregnancy compared with progesterone + oestrogen (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.12 [0.91, 1.38]
  9 studies · 1651 participants
  Low

Progesterone vs progesterone + oestrogen

Progesterone showed no clear difference in clinical pregnancy compared with progesterone + oestrogen (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.86 [0.72, 1.04]
  14 studies · 2169 participants
  Low

Progesterone vs progesterone + GnRH agonist

It is very uncertain whether progesterone changes live birth or ongoing pregnancy compared with progesterone + GnRH agonist (very low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.62 [0.48, 0.81]
  9 studies · 2861 participants
  Very low

Progesterone vs progesterone + GnRH agonist

Progesterone may leads to lower clinical pregnancy compared with progesterone + GnRH agonist (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.66 [0.51, 0.85]
  8 studies · 2435 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes live birth or ongoing pregnancy IM vs oral (very low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.71 [0.14, 3.66]
  1 study · 40 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes live birth or ongoing pregnancy IM vs vaginal/rectal (very low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.24 [1.03, 1.5]
  7 studies · 2309 participants
  Very low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Vaginal/rectal vs oral (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.19 [0.83, 1.69]
  4 studies · 857 participants
  Low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Low dose vaginal vs high dose vaginal (moderate certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.97 [0.84, 1.11]
  5 studies · 3720 participants
  Moderate

hCG vs placebo/no treatment

It is very uncertain whether hCG changes clinical pregnancy compared with placebo/no treatment (very low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.3 [0.9, 1.88]
  5 studies · 746 participants
  Very low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Short protocol vs long protocol (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.04 [0.79, 1.36]
  5 studies · 1205 participants
  Low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Micronised vs synthetic (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.9 [0.53, 1.55]
  2 studies · 470 participants
  Low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Vaginal ring vs vaginal gel (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 1.09 [0.88, 1.36]
  1 study · 1271 participants
  Low

Intervention not reported

The intervention showed no clear difference in live birth or ongoing pregnancy Subcutaneous vs vaginal gel (low certainty).

• Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
  OR 0.92 [0.74, 1.14]
  2 studies · 1465 participants
  Low