Progestogen therapy (luteal phase only) vs other medical therapy
Menstrual blood loss: mean loss · women with heavy menstrual bleeding
1 finding from 1 review
- no estimate extracted4 studies · 145 participantsLow
Findings
What do systematic reviews say?
1,266 questions · 1,314 findings · 160 reviews · Headline outcomes only
No studies found 309 · 23.5%GRADE not reported 34 · 2.6%Very low 356 · 27.1%Low 393 · 29.9%Moderate 187 · 14.2%High 35 · 2.7%
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Quality of life · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Adverse effects: headache · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) showed no clear difference in adverse effect Headache compared with other medical therapy (low certainty).
1 finding from 1 review
- OR 1.45 [0.4, 5.31]2 studies · 189 participantsLow
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Adverse effect Breakthrough bleeding/spotting · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) may leads to lower adverse effect Breakthrough bleeding/spotting compared with other medical therapy (low certainty).
1 finding from 1 review
- OR 0.18 [0.06, 0.55]3 studies · 220 participantsLow
Progestogen therapy (luteal phase only) vs other medical therapy
Satisfaction · women with heavy menstrual bleeding
It is very uncertain whether progestogen therapy (luteal phase only) changes satisfaction compared with other medical therapy (very low certainty).
1 finding from 1 review
- OR 0.8 [0.17, 3.8]1 study · 52 participantsVery low
Progestogen therapy (luteal phase only) vs other medical therapy
Days of bleeding · women with heavy menstrual bleeding
1 finding from 1 review
- no estimate extracted5 studies · 171 participantsVery low
Progestogen therapy (luteal phase only) vs other medical therapy
Physical functioning component of health‐related quality of life, measured using various scales · women with heavy menstrual bleeding
1 finding from 1 review
- no estimate extracted1 study · 62 participantsVery low
Progestogen therapy (luteal phase only) vs other medical therapy
Total adverse effects · women with heavy menstrual bleeding
It is very uncertain whether progestogen therapy (luteal phase only) changes total adverse effects compared with other medical therapy (very low certainty).
1 finding from 1 review
- OR 0.68 [0.36, 1.28]5 studies · 197 participantsVery low
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Menstrual blood loss PBAC score · women with heavy menstrual bleeding
2 findings from 1 review
- no estimate extracted4 studies · 355 participantsVery low
- no estimate extracted1 study · 76 participantsLow
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Satisfaction · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) may leads to lower satisfaction compared with other medical therapy (low certainty).
1 finding from 1 review
- OR 0.31 [0.13, 0.71]1 study · 95 participantsLow
Progestogen therapy long cycle (3 to 4 weeks) vs other medical therapy
Days of bleeding · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Decompressive craniectomy vs medical treatment
Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyRR 0.663 studies · 571 participantsModerate
Decompressive craniectomy vs medical treatment
Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyRR 0.59 [0.45, 0.76]1 study · 373 participantsHigh
Decompressive craniectomy vs medical treatment
'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyRR 13 studies · 571 participantsLow
Decompressive craniectomy vs medical treatment
'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyRR 0.95 [0.83, 1.09]1 study · 373 participantsHigh
Decompressive craniectomy vs medical treatment
Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 182 participantsModerate
Decompressive craniectomy vs medical treatment
Adverse events assessed in various ways, up to 24 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
1 finding from 1 review
- Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 544 participantsLow
The introduction of advanced or specialist nurses to the nursing workforce vs usual staffing
Nursing‐staff turnover · medical patients and patients with cancer, asthma, diabetes, heart failure and chronic illness
The review found no eligible studies for this question.
1 finding from 1 review
- Hospital nurse‐staffing models and patient‐ and staff‐related outcomes 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Primary nursing vs usual/team/functional nursing
Nursing‐staff turnover · nurses working on medical or long‐term psychiatric units
1 finding from 1 review
- Hospital nurse‐staffing models and patient‐ and staff‐related outcomes 2019 · Cochrane Headline outcomes onlyno estimate extracted464 participantsVery low
Primary nursing vs usual/team/functional nursing
Patient mortality · nurses working on medical or long‐term psychiatric units
The review found no eligible studies for this question.
1 finding from 1 review
- Hospital nurse‐staffing models and patient‐ and staff‐related outcomes 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found