Findings

What do systematic reviews say?

859 questions · 901 findings · 80 reviews

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No studies found 247 · 27.4%GRADE not reported 170 · 18.9%Very low 224 · 24.9%Low 136 · 15.1%Moderate 90 · 10%High 34 · 3.8%

foam dressing vs hydrocapillary dressing

Health‐related quality of life · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

foam dressing vs hydrocolloid dressing

Ulcer healing · people with venous leg ulcers

2 findings from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 1 [0.81, 1.22]
5 studies · 418 participants
Moderate

foam dressing vs hydrocolloid dressing

Change in ulcer size · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

foam dressing vs hydrocolloid dressing

Proportion of participants experiencing adverse events · people with venous leg ulcers

foam dressing showed no clear difference in proportion of participants experiencing adverse events compared with hydrocolloid dressing (low certainty).

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 1.22 [0.64, 2.31]
1 study · 107 participants
Low

foam dressing vs hydrocolloid dressing

Health‐related quality of life · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

foam dressing vs knitted viscose dressing

Ulcer healing · people with venous leg ulcers

2 findings from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 1.35 [0.89, 2.05]
1 study · 132 participants
Low

foam dressing vs knitted viscose dressing

Change in ulcer size · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

foam dressing vs knitted viscose dressing

Proportion of participants experiencing adverse events · people with venous leg ulcers

foam dressing showed no clear difference in proportion of participants experiencing adverse events compared with knitted viscose dressing (low certainty).

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 5 [0.24, 102.19]
1 study · 132 participants
Low

foam dressing vs knitted viscose dressing

Health‐related quality of life · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

polyurethane foam dressing vs hydrocellular foam dressing

Change in ulcer size · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

polyurethane foam dressing vs hydrocellular foam dressing

Proportion of participants experiencing adverse events · people with venous leg ulcers

polyurethane foam dressing showed no clear difference in proportion of participants experiencing adverse events compared with hydrocellular foam dressing (low certainty).

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 1.13 [0.69, 1.85]
1 study · 156 participants
Low

polyurethane foam dressing vs hydrocellular foam dressing

Health‐related quality of life · people with venous leg ulcers

1 finding from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

foam dressing vs paraffin gauze

Ulcer healing · people with venous leg ulcers

2 findings from 1 review

Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Foam dressings for venous leg ulcers 2013 · Cochrane Headline outcomes only
RR 1.34 [0.61, 2.92]
1 study · 71 participants
Low

Levamisole (150 mg per day) vs placebo

Relief of pain · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Levamisole (150 mg per day) showed no clear difference in decrease in pain compared with placebo; GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
RR 4.29 [0.67, 27.24]
1 study
GRADE not reported

Multivitamin vs placebo

Average mouth pain during RAS episodes · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Daily multivitamin showed no clear difference in average mouth pain during RAS episodes compared with placebo; GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
MD -0.05 [-0.71, 0.61]
1 study
GRADE not reported

Levamisole (150 mg per day) vs placebo

Decrease in frequency of attacks · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Levamisole (150 mg per day) showed no clear difference in decrease in frequency of attacks compared with placebo; GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
RR 4.29 [0.72, 25.39]
1 study
GRADE not reported

Levamisole (150 mg per day) vs placebo

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
Patients receiving levamisole reported more adverse effects than those receiving placebo (mild stomach upset/nausea, diarrhoea, sleeplessness, dysgeusia/dysosmia), however no adverse effects were reported as requiring…
8 studies
GRADE not reported

Prednisone (oral, commencing 25 mg with phased dose reduction over 2 months) vs placebo

Time to resolution of first ulcer (days) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Prednisone (oral, commencing 25 mg with phased dose reduction over 2… led to lower time to resolution of first ulcer (days) compared with placebo; GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
2 months
MD -6.35 [-6.74, -5.96]
1 study · 40 participants
GRADE not reported

Rofecoxib (oral, 50 mg on first day then 25 to 50 mg per day for 4 days) vs Tinidazole (1 g per day for 3 days)

Total effective rate at 4 days · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Rofecoxib (oral, 50 mg on first day then 25 to 50 mg per day for 4… showed no clear difference in total effective rate at 4 days compared with tinidazole (1 g per day for 3 days); GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
4 days
RR 1.17 [0.95, 1.43]
1 study · 60 participants
GRADE not reported

Bee propolis (one 500 mg capsule per day) vs placebo

Quality of life · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
6 months (minimum)
Patients in the propolis group self-reported a significant improvement in their quality of life (P=0.03), based on volunteered statements of self-reported improvement.
1 study · 19 participants
GRADE not reported