Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

592 questions · 604 findings · 53 reviews · Headline outcomes only

No studies found 151 · 25%GRADE not reported 31 · 5.1%Very low 94 · 15.6%Low 170 · 28.1%Moderate 114 · 18.9%High 44 · 7.3%

Summary of findings: Protein supplements vs no intervention

Diarrhoea (grade 2+) · People undergoing RT for pelvic cancer

It is very uncertain whether summary of findings: Protein supplements changes diarrhoea (grade 2+) compared with no intervention (very low certainty).

1 finding from 1 review

Intervention not reported

Mortality sensitivity analysis (calculated instead of overall survival) ‐ without UK NCRI Rapid trial and MSKCC trial #90‐44due to high risk of other bias

The intervention probably leads to lower mortality sensitivity analysis (calculated instead of overall… (moderate certainty).

1 finding from 1 review

Chemotherapy plus involved‐field radiation vs same chemotherapy plus extended‐field radiation

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (early stages)

Chemotherapy plus involved‐field radiation showed no clear difference in secondary malignant neoplasms compared with same chemotherapy plus extended‐field radiation (low certainty).

1 finding from 1 review