Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,935 questions · 1,986 findings · 260 reviews · Headline outcomes only

No studies found 503 · 25.3%GRADE not reported 76 · 3.8%Very low 593 · 29.9%Low 509 · 25.6%Moderate 241 · 12.1%High 64 · 3.2%

Multifactorial interventions vs usual care or attention control

Number of people sustaining recurrent falls (defined as two or more falls in a specified time period) · Older people living in the community

Multifactorial interventions showed no clear difference in number of people sustaining recurrent falls (defined as 2 or more… compared with usual care or attention control (low certainty).

1 finding from 1 review

Multifactorial interventions vs usual care or attention control

Number of people who experience a fall that required hospital admission · Older people living in the community

Multifactorial interventions showed no clear difference in number of people who experience a fall that required hospital… compared with usual care or attention control (low certainty).

1 finding from 1 review

Multifactorial interventions vs usual care or attention control

Number of people who experience a fall that required medical attention · Older people living in the community

Multifactorial interventions showed no clear difference in number of people who experience a fall that required medical attention compared with usual care or attention control (low certainty).

1 finding from 1 review

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Polyvinylpyrrolidone + zinc oxide · people with pressure ulcers

NMA evidence for individual network: proportion with complete… showed no clear difference in polyvinylpyrrolidone + zinc oxide compared with saline gauze (low certainty).

1 finding from 1 review

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Combination silicone foam dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes combination silicone foam dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Physical ergonomic intervention vs alternative instrument design

Self‐reported complaints of MSD pain in right upper extremity – elbow, forearm (0‐ to 10‐point scale; 0 = no pain, 10 = unbearable pain) · Dentists and dental hygienists who performed scaling, root planing, or dental prophylaxis procedures
1 finding from 1 review

Summary of findings table (subcomparison 3): chemotherapy agent(s) plus control intervention vs control intervention

Overall survival · palliative participants with esophageal and GE‐junction carcinoma

Summary of findings table (subcomparison 3): chemotherapy agent(s)… probably leads to lower overall survival compared with control intervention alone (moderate certainty).

1 finding from 1 review

Summary of findings table (subcomparison 3): chemotherapy agent(s) plus control intervention vs control intervention

Toxicity · palliative participants with esophageal and GE‐junction carcinoma

It is very uncertain whether summary of findings table (subcomparison 3): chemotherapy agent(s)… changes toxicity compared with control intervention alone (very low certainty).

1 finding from 1 review