Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

660 questions · 679 findings · 99 reviews · Headline outcomes only

No studies found 160 · 23.6%GRADE not reported 17 · 2.5%Very low 199 · 29.3%Low 189 · 27.8%Moderate 97 · 14.3%High 17 · 2.5%

Anticipated normal responders: higher vs lower dose of FSH

225/200 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in 225/200 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

IU vs 225 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in IU vs 225 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Live birth · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in live Birth compared with c‐IVF (low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Multiple pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in multiple Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Ectopic pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in ectopic Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Pre‐eclampsia · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in pre‐Eclampsia compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Prematurity · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in prematurity compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Clinical pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in clinical Pregnancy compared with c‐IVF (low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Viable intrauterine Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in viable intrauterine Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Miscarriage · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in miscarriage compared with c‐IVF (moderate certainty).

1 finding from 1 review