Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

864 questions · 895 findings · 140 reviews · Headline outcomes only

No studies found 202 · 22.6%GRADE not reported 53 · 5.9%Very low 227 · 25.4%Low 254 · 28.4%Moderate 131 · 14.6%High 28 · 3.1%

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI related to cardiac or general surgery · patients with AKI who need CRRT

Intensive leads to lower mortality: patients with AKI related to cardiac or general surgery compared with less intensive continuous renal replacement therapy (CRRT) (high certainty).

1 finding from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI not related to surgery · patients with AKI who need CRRT

Intensive showed no clear difference in mortality: patients with AKI not related to surgery compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).

1 finding from 1 review