Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 674 findings · 44 reviews · All outcomes

No studies found 253 · 37.5%GRADE not reported 258 · 38.3%Very low 106 · 15.7%Low 38 · 5.6%Moderate 15 · 2.2%High 4 · 0.6%

Metronidazole + SRP vs Amoxicillin + metronidazole + SRP

Probing pocket depth · Adults with periodontitis (chronic and aggressive)

Metronidazole + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.

2 findings from 1 review

Metronidazole + SRP vs SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.

3 findings from 1 review

Metronidazole + SRP vs Amoxicillin + metronidazole + SRP

Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)

Metronidazole + SRP showed no clear difference in percentage of bleeding on probing (BOP) compared with amoxicillin + metronidazole + SRP; GRADE not reported.

2 findings from 1 review

Moxifloxacin + SRP vs SRP

Percentage of bleeding on probing (BOP) · Adults with chronic periodontitis

Moxifloxacin + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.

2 findings from 1 review