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Evidence found and GRADE certainty

627 questions · 638 findings · 45 reviews

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No studies found 89 · 13.9%GRADE not reported 37 · 5.8%Very low 221 · 34.6%Low 181 · 28.4%Moderate 92 · 14.4%High 18 · 2.8%

Intervention not reported

Acceptability of treatment (17 weeks) · women with a history of postnatal depression
1 finding from 1 review

Intervention not reported

Overall maternal satisfaction (17 weeks) · women with a history of postnatal depression

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Improvement in the maternal relationship with the baby (17 weeks) · women with a history of postnatal depression

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Establishment or continuation of breastfeeding (17 weeks) · women with a history of postnatal depression

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Postnatal depression (17 weeks) · women with a history of postnatal depression

It is very uncertain whether the intervention changes postnatal depression (17 weeks) (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects experienced by mother and/or fetus or nursing baby · women with a history of postnatal depression
1 finding from 1 review

Intervention not reported

Acceptability of treatment (17 weeks) · women with a history of postnatal depression
1 finding from 1 review

Selective serotonin reuptake inhibitors vs tricyclic antidepressants (TCAs)

Adverse effects during antidepressant treatment period (0‐12 weeks) · adults living with HIV and depression

It is very uncertain whether selective serotonin reuptake inhibitors (SSRI) changes adverse effects during antidepressant treatment period (0‐12 weeks) compared with tricyclic antidepressant (TCA) (very low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors vs atypical agent

Improvement in depression at 6‐12 weeks: HAM‐D score (dichotomized) · adults living with HIV and depression

Selective serotonin reuptake inhibitor (SSRI) showed no clear difference in improvement in depression at 6‐12 weeks: HAM‐D score (dichotomized) compared with atypical agent (low certainty).

1 finding from 1 review

Selective serotonin reuptake inhibitors vs atypical agent

Improvement in depression at 6‐12 weeks: CGI‐I (score of 1 or 2) · adults living with HIV and depression

Selective serotonin reuptake inhibitor (SSRI) showed no clear difference in improvement in depression at 6‐12 weeks: CGI‐I (score of 1 or 2) compared with atypical agent (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Improvement in depression at 6‐12 weeks: HAM‐D score (dichotomized) · adults living with HIV and depression

Antidepressant showed no clear difference in improvement in depression: HAM‐D score at 6‐12 weeks (dichotomized) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Improvement in depression at 6‐12 weeks: CGI‐I (score of 1 or 2) · adults living with HIV and depression

Antidepressant showed no clear difference in improvement in depression at 6‐12 weeks: CGI‐I (score of 1 or 2) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Adverse effects during antidepressant treatment period (0‐12 weeks) · adults living with HIV and depression

It is very uncertain whether antidepressant changes adverse effects during antidepressant treatment period (0‐12 weeks) compared with placebo (very low certainty).

1 finding from 1 review