Intervention not reported
Serum/plasma creatinine levels (μmol/L) after treatment Normal values for male and female newborns 17.7 to 88.4 µmol/L · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in serum/plasma creatinine levels (μmol/L) after treatment Normal… (low certainty).
1 finding from 1 review
Intervention not reported
Oliguria (Urine output < 1 mL/kg/hour) · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in oliguria (Urine output < 1 mL/kg/hour) (low certainty).
1 finding from 1 review
Intervention not reported
Failure to close a patent ductus arteriosus after 3 doses of ibuprofen · preterm infants with patent ductus arteriosus
The intervention probably leads to lower failure to close a patent ductus arteriosus after 3 doses of ibuprofen (moderate certainty).
1 finding from 1 review
Intervention not reported
Necrotising enterocolitis · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in necrotising enterocolitis (low certainty).
1 finding from 1 review
Intervention not reported
Necrotising enterocolitis · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in necrotising enterocolitis (moderate certainty).
1 finding from 1 review
Intervention not reported
Oliguria · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in oliguria (low certainty).
1 finding from 1 review
Intervention not reported
Failure to close a patent ductus arteriosus (PDA) (after single or 3 doses) · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in failure to close a patent ductus arteriosus (PDA) (after single or 3… (moderate certainty).
1 finding from 1 review
Intervention not reported
Need for surgical closure of the PDA · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in need for surgical closure of the PDA (moderate certainty).
1 finding from 1 review
Intervention not reported
Duration of ventilator support (days) · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in duration of ventilator support (days) (moderate certainty).
1 finding from 1 review
Intervention not reported
Necrotising enterocolitis (any stage) · preterm infants with patent ductus arteriosus
The intervention probably leads to lower necrotising enterocolitis (any stage) (moderate certainty).
1 finding from 1 review
Intervention not reported
Oliguria (urine output < 1 mL/kg/hour) · preterm infants with patent ductus arteriosus
The intervention probably leads to lower oliguria (urine output < 1 mL/kg/hour) (moderate certainty).
1 finding from 1 review
Intervention not reported
Serum/plasma creatinine levels (μmol/L) · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in serum/plasma creatinine levels (μmol/L) (low certainty).
1 finding from 1 review
Intervention not reported
Failure to close a patent ductus arteriosus (PDA) (after 3 doses) · preterm infants with patent ductus arteriosus
The intervention showed no clear difference in failure to close a patent ductus arteriosus (PDA) (after 3 doses) (low certainty).
1 finding from 1 review
Neonatal mortality · neonates with sepsis
Comparison 1: community‐based antibiotic delivery may leads to lower neonatal mortality compared with standard care (low certainty).
1 finding from 1 review
Neonatal mortality · neonates with sepsis
Comparison 1: antibiotic alone or antibiotic with other newborn care… showed no clear difference in neonatal mortality ‐ antibiotics alone compared with standard care (moderate certainty).
2 findings from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in neonatal mortality compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in treatment failure compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: 7 days oral amoxicillin + injectable gentamicin showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
Early neonatal mortality · neonates with possible serious bacterial infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found