Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,100 questions · 1,164 findings · 107 reviews

No studies found 280 · 24.1%GRADE not reported 159 · 13.7%Very low 292 · 25.1%Low 274 · 23.5%Moderate 113 · 9.7%High 46 · 4%

Alpha‐lipoic acid vs placebo

Change in taste · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs information only

Percentage of participants reaching PASI 75 · psoriasis

Dietary intervention and exercise programme showed no clear difference in severity of psoriasis PASI 75 (the proportion of participants… compared with information only (moderate certainty).

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Adverse effects: exacerbation of symptoms · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: exacerbation of symptoms compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: drowsiness compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Adverse effects: insomnia · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: insomnia compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
  • Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
    short-term (up to 3 months) · Catuama
    'Catuama' herbal compound (Spanemberg 2012) contributes to the dietary supplements short-term symptom-relief comparison (insufficient/contradictory); no separate estimate reported.
    1 study · 72 participants
    GRADE not reported

Dietary supplements (Catuama herbal compound) vs placebo

Weight gain · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: weight gain compared with placebo (very low certainty).

1 finding from 1 review