What do systematic reviews say?

Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel

• Interventions for rosacea 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 91 participants
  Low

Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel

• Interventions for rosacea 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 91 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes failure rate of post‐pyloric placement of the enteral feeding tube… (very low certainty).

• Metoclopramide for post‐pyloric placement of naso‐enteral feeding tubes 2015 · Cochrane Headline outcomes only
  RR 0.82 [0.61, 1.1]
  4 studies · 204 participants
  Very low

Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR)

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA)

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziectomy (T)

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T)

The review found no eligible studies for this question.

• Surgery for thumb (trapeziometacarpal joint) osteoarthritis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in glasgow Outcome Score (GOS) Clinical assessment (moderate certainty).

• Cooling for cerebral protection during brain surgery 2015 · Cochrane Headline outcomes only
  RR 0.8 [0.61, 1.04]
  4 studies · 1216 participants
  Moderate

Preoperative vessel imaging by ultrasound mapping vs standard preoperative care

Preoperative vessel imaging by ultrasound mapping showed no clear difference in fistulas matured Clinical assessment by experienced HD nurse⁴ compared with standard preoperative care (low certainty).

• Preoperative vascular access evaluation for haemodialysis patients 2015 · Cochrane Headline outcomes only
  RR 1.11 [0.98, 1.25]
  3 studies · 356 participants
  Low

Preoperative vessel imaging by ultrasound mapping vs standard preoperative care

Preoperative vessel imaging by ultrasound mapping showed no clear difference in fistulas used for dialysis Clinical assessment by HD nurse compared with standard preoperative care (low certainty).

• Preoperative vascular access evaluation for haemodialysis patients 2015 · Cochrane Headline outcomes only
  RR 1.12 [0.99, 1.28]
  2 studies · 286 participants
  Low

Ketoconazole vs placebo

Ketoconazole may leads to lower failure to achieve complete resolution Clinical assessment compared with placebo (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 0.69 [0.59, 0.81]
  8 studies · 2520 participants
  Low

Ketoconazole vs steroids

Ketoconazole showed no clear difference in failure to achieve complete resolution (combined for face and scalp)… compared with steroids (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.17 [0.95, 1.44]
  6 studies · 302 participants
  Low

Ketoconazole vs steroids

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 80 participants
  Very low

Ketoconazole vs ciclopirox

Ketoconazole showed no clear difference in failure to achieve complete resolution ‐ Face only Clinical assessment compared with ciclopirox (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.09 [0.95, 1.26]
  3 studies · 447 participants
  Low

Ketoconazole vs ciclopirox

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 1.16 [0.98, 1.38]
  2 studies · 339 participants
  Low

Ciclopirox vs placebo

Ciclopirox probably leads to lower failure to achieve complete resolution (combined for face and scalp)… compared with placebo (moderate certainty).

• Topical antifungals for seborrhoeic dermatitis 2015 · Cochrane Headline outcomes only
  RR 0.79 [0.67, 0.94]
  8 studies · 1525 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

• Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Low

Intervention not reported

• Cholinesterase inhibitors for rarer dementias associated with neurological conditions 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 24 participants
  Low