Cochrane · systematic review · CD006638

Cooling for cerebral protection during brain surgery

Galvin, IM, Levy, R, Boyd, JG, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 3 · 50%High 2 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Cooling for cerebral protection during brain surgery

Population: cerebral protection during brain surgery
6 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality rate Risk ratio
RR 0.87 [0.59, 1.27]4 studies · 1216 participantsModerate
Downgraded: risk of bias
Glasgow Outcome Score (GOS) Clinical assessment
RR 0.8 [0.61, 1.04]4 studies · 1216 participantsModerate
Downgraded: risk of bias
Ischaemic stroke ‐ cooled during Clinical examination supported by imaging evidence
RR 0.93 [0.82, 1.05]2 studies · 1114 participantsHigh
Infections Unstated means
RR 1.2 [0.73, 1.97]3 studies · 1194 participantsLow
Downgraded: inconsistency
Congestive heart failure ‐ cooled during
RR 0.85 [0.6, 1.21]2 studies · 1114 participantsHigh
Myocardial infarction
RR 1.86 [0.69, 4.98]3 studies · 1139 participantsModerate
Downgraded: risk of bias