Adverse events · Adults with chronic periodontitis
Moxifloxacin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse effects · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.59 [-1.27, 0.08]
2 studies · 110 participants
Very low
MD -0.43 [-0.77, -0.10]
7 studies · 258 participants
GRADE not reported
MD -0.51 [-0.83, -0.19]
6 studies · 216 participants
GRADE not reported
Swelling (mean) · Adults with mandibular third molars requiring removal
Coronectomy showed no clear difference in swelling (mean) compared with complete extraction (odontectomy); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
It is very uncertain whether high-volume irrigation (~175 mL) changes alveolar osteitis compared with low-volume irrigation (~25 mL) (very low certainty).
1 finding from 1 review
Patient-reported quality of life changes · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether mechanical (high-volume) irrigation changes wound infection compared with manual (low-volume) irrigation (very low certainty).
1 finding from 1 review
Permanent altered sensation (inferior alveolar nerve damage) · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Levofloxacin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
The only included trial (Dukic 2016) reported nausea, dizziness and/or anorexia in the cefixime + SRP group.
1 study · 60 participants
GRADE not reported
Percentage of bleeding on probing (BOP) · Adults with chronic periodontitis
Cefixime + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.
1 finding from 1 review
Antimicrobial resistance · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Antimicrobial resistance · Adults with chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether primary (complete) wound closure changes wound infection compared with secondary (partial) wound closure (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review