Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

573 questions · 608 findings · 115 reviews

No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Protocol‐directed sedation management vs usual care

Adverse event ‐ incidence of self‐extubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management

Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of self‐extubation (in ICU) compared with usual care (high certainty).

1 finding from 1 review

Protocol‐directed sedation management vs usual care

Adverse event ‐ incidence of reintubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management

Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of reintubation (in ICU) compared with usual care (low certainty).

1 finding from 1 review

Protocol‐directed sedation management vs usual care

Incidence of tracheostomy (in ICU) · mechanically ventilated ICU adults and children requiring sedation management

Protocol‐directed sedation management showed no clear difference in incidence of tracheostomy (in ICU) compared with usual care (low certainty).

1 finding from 1 review

Physical and cognitive therapy vs usual care

Duration of ICU stay · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…

It is very uncertain whether physical and cognitive therapy changes length of ICU stay (days) compared with standard care (very low certainty).

1 finding from 1 review

Physical and cognitive therapy vs usual care

Cognitive functioning b) Executve functioning (DEX score) (scores range from 0 to 80. Lower scores indicate better functioning) (DEX) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review

HALOPERIDOL vs placebo

In‐hospital mortality within 28 days. · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

Haloperidol showed no clear difference in in‐hospital mortality within 28 days. compared with placebo (moderate certainty).

1 finding from 1 review

Physical and cognitive therapy vs usual care

In‐hospital mortality at 30 days or at the longest · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…

It is very uncertain whether physical and cognitive therapy changes in‐hospital mortality at 30 days or at the longest compared with standard care (very low certainty).

1 finding from 1 review

Early intervention (mobilization or active exercise) vs usual care

Physical function ‐ return to independent functional status at hospital discharge Defined as ability to perform 6 ADLs (bathing, dressing, eating, grooming, transferring from bed to chair, using the toilet) and walk independently, · critically ill, mechanically ventilated adults

Early intervention (mobilization or active exercise) may leads to higher physical function ‐ return to independent functional status at… compared with usual care (low certainty).

1 finding from 1 review

Early intervention (mobilization or active exercise) vs usual care

Physical function · critically ill, mechanically ventilated adults
3 findings from 1 review