Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

518 questions · 558 findings · 63 reviews

No studies found 77 · 13.8%GRADE not reported 143 · 25.6%Very low 89 · 15.9%Low 137 · 24.6%Moderate 95 · 17%High 17 · 3%

Flunarizine vs placebo

Recurrence of stroke at the end of · people with acute ischemic stroke

Flunarizine showed no clear difference in recurrence of stroke at the end of compared with placebo (low certainty).

1 finding from 1 review

Flunarizine vs placebo

Adverse events during treatment period · people with acute ischemic stroke

Flunarizine may leads to higher adverse events during treatment period compared with placebo (low certainty).

1 finding from 1 review

Isradipine vs placebo

Death or dependency at end of · people with acute ischemic stroke

Isradipine showed no clear difference in death or dependency at end of compared with placebo (low certainty).

1 finding from 1 review

Isradipine vs placebo

Death at the end of · people with acute ischemic stroke

Isradipine showed no clear difference in death at the end of compared with placebo (low certainty).

1 finding from 1 review

Nimodipine vs placebo

Death or dependency at end of · people with acute ischemic stroke

Nimodipine showed no clear difference in death or dependency at end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Death at the end of treatment · people with acute ischemic stroke

Nimodipine showed no clear difference in death at the end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia ‐ not improved to a clinically important extent · people with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether the intervention changes tardive dyskinesia ‐ not improved to a clinically important extent (very low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia ‐ deterioration · people with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse effects ‐ important extrapyramidal adverse effects · people with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Acceptability of treatment ‐ leaving the study early · people with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Social confidence, social inclusion, social networks or personalised quality of life measures ‐ no clinically significant change · people with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review