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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,518 questions in 135 reviews · Infectious Diseases
current versionsNo studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR CL cases > 12 months · People at risk of CL or VL Vector and reservoir control for preventing leishmaniasis (2015) · Cochrane | RR 0.31 [0.18, 0.53] | 2 studies · 10579 participants | Low |
Intervention NR VL cases > 2 years · People at risk of CL or VL Vector and reservoir control for preventing leishmaniasis (2015) · Cochrane | RR 0.99 [0.46, 2.15] | 1 study · 19810 participants | Moderate |
Intervention NR Vector density · People at risk of CL or VL Vector and reservoir control for preventing leishmaniasis (2015) · Cochrane | no estimate extracted | 1 study · 1 participants | Low |
Intervention NR CL cases > 12 months · People at risk of CL or VL Vector and reservoir control for preventing leishmaniasis (2015) · Cochrane | RR 0 [0, 0.49] | 1 study · 2938 participants | Low |
Intervention NR VL cases > 2 years · People at risk of CL or VL Vector and reservoir control for preventing leishmaniasis (2015) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Death or hospital admission · Children with anaemia Intermittent preventive antimalarial treatment for children with anaemia (2015) · Cochrane | RR 0.9 [0.71, 1.13] | 3 studies · 3160 participants | Moderate |
Intervention NR Children with anaemia (Hb < 11 g/dL) · Children with anaemia Intermittent preventive antimalarial treatment for children with anaemia (2015) · Cochrane | RR 0.97 [0.88, 1.07] | 4 studies · 2237 participants | Moderate |
Intervention NR Mean change in Hb from baseline · Children with anaemia Intermittent preventive antimalarial treatment for children with anaemia (2015) · Cochrane | no estimate extracted | 4 studies · 1672 participants | Moderate |
Intervention NR Mean Hb · Children with anaemia Intermittent preventive antimalarial treatment for children with anaemia (2015) · Cochrane | no estimate extracted | 4 studies · 1672 participants | Low |
Artemisinin‐naphthoquine vs AL Treatment failure at day 28 · Adults and children with uncomplicated P. falciparum malaria Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria (2015) · Cochrane | RR 1.02 [0.24, 4.37] | 3 studies · 487 participants | Low |
Artemisinin‐naphthoquine vs AL Treatment failure at day 42 · Adults and children with uncomplicated P. falciparum malaria Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria (2015) · Cochrane | RR 0.09 [0, 1.59] | 1 study · 186 participants | Very low |
Artemisinin‐naphthoquine vs DHA‐P Treatment failure at day 28 · Adults and children with uncomplicated P. falciparum malaria Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria (2015) · Cochrane | no estimate extracted | 1 study · 143 participants | Very low |
Artemisinin‐naphthoquine vs DHA‐P Treatment failure at day 42 · Adults and children with uncomplicated P. falciparum malaria Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria (2015) · Cochrane | RR 0.91 [0.13, 6.26] | 1 study · 143 participants | Very low |
Praziquantel 40 mg/kg vs placebo Parasitological failure At 1 to 2 months · People with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.42 [0.29, 0.59] | 7 studies · 864 participants | High |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Haematuria · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.89 [0.47, 1.67] | 1 study · 117 participants | Very low |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Proteinuria · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.85 [0.34, 2.12] | 1 study · 117 participants | Very low |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Adverse events · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 8 studies · 992 participants | Low |
Praziquantel 40 mg/kg multiple doses vs single dose Parasitological failure At 2 years · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 2.71 [1.47, 5] | 1 study · 62 participants | Very low |
Praziquantel 40 mg/kg multiple doses vs single dose Mean percent egg reduction At 2 years · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 1 study · 62 participants | Very low |
Praziquantel 40 mg/kg multiple doses vs single dose Parasitological failure At 3 years · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.92 [0.59, 1.42] | 1 study · 43 participants | Very low |
Praziquantel 40 mg/kg multiple doses vs single dose Haematuria At 3 years · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.7 [0.42, 1.17] | 1 study · 43 participants | Very low |
Praziquantel 40 mg/kg multiple doses vs single dose Adverse events · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 1 study · 43 participants | Very low |
Metrifonate 3 x 7.5 mg/kg given two weeks apart vs placebo Parasitological failure At 2 to 2.5 months · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.41 [0.3, 0.56] | 1 study · 93 participants | Low |
Metrifonate 3 x 7.5 mg/kg given two weeks apart vs placebo Mean percent egg reduction At 2 to 2.5 months · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 1 study · 93 participants | Low |
Praziquantel 40 mg/kg vs placebo Percentage egg reduction At 1 to 2 months · People with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 6 studies · 678 participants | High |
Metrifonate 3 x 7.5 mg/kg given two weeks apart vs placebo Parasitological failure At 6 months · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.3 [0.24, 0.37] | 1 study · 400 participants | Moderate |
Metrifonate 3 x 7.5 mg/kg given two weeks apart vs placebo Mean percent egg reduction At 6 months · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 1 study · 400 participants | Moderate |
Metrifonate 3 x 7.5 mg/kg given two weeks apart vs placebo Adverse events · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 2 studies · 493 participants | Ungraded |
Artesunate vs placebo Parasitological failure At 8 weeks · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.53 [0.16, 1.71] | 2 studies · 251 participants | Very low |
Artesunate vs placebo Mean percent egg reduction At 8 weeks · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 2 studies · 276 participants | Low |
Artesunate vs placebo Microhaematuria At 8 weeks · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 1.22 [0.85, 1.76] | 1 study · 119 participants | Low |
Artesunate vs placebo Adverse events · patients with treating urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 2 studies · 276 participants | Low |
Praziquantel and artesunate vs praziquantel Parasitological failure at 8 weeks · patients with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.62 [0.38, 0.99] | 2 studies · 265 participants | Low |
Praziquantel and artesunate vs praziquantel Percent egg reduction · patients with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 2 studies · 265 participants | Very low |
Praziquantel and artesunate vs praziquantel Microhaematuria · patients with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.69 [0.4, 1.18] | 1 study · 177 participants | Low |
Praziquantel 40 mg/kg vs placebo Microhaematuria At 8 weeks · People with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.53 [0.33, 0.84] | 1 study · 119 participants | Low |
Praziquantel and artesunate vs praziquantel Adverse events · patients with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 1 study · 156 participants | Very low |
Praziquantel 40 mg/kg vs placebo Haemoglobin At 6 to 8 months · People with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 2 studies · 727 participants | Moderate |
Praziquantel 40 mg/kg vs placebo Adverse events · People with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 9 studies · 1591 participants | Low |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Parasitological failure At 1 month · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.76 [0.59, 0.99] | 4 studies · 401 participants | Low |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Mean percent egg reduction At 1 month · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 4 studies · 362 participants | Low |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Parasitological failure At 6 months · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | RR 0.97 [0.76, 1.23] | 6 studies · 669 participants | Moderate |
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose Mean percent egg reduction At 6 months · people with urinary schistosomiasis Drugs for treating urinary schistosomiasis (2014) · Cochrane | no estimate extracted | 4 studies · 362 participants | Low |
Intervention NR Mortality All‐cause death · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 1.15 [0.44, 3.06] | 3 studies · 2097 participants | Very low |
Intervention NR Neonatal mortality · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.62 [0.37, 1.05] | 2 studies · 2156 participants | Low |
Intervention NR Preterm birth · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.85 [0.66, 1.1] | 2 studies · 1493 participants | Low |
Intervention NR Low birthweight · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.73 [0.61, 0.87] | 8 studies · 3619 participants | Moderate |
Intervention NR Mean birthweight · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | no estimate extracted | 9 studies · 3936 participants | Moderate |
Intervention NR Placental parasitaemia · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.54 [0.43, 0.69] | 7 studies · 2830 participants | High |
Intervention NR Cord blood haemoglobin · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | no estimate extracted | 1 study · 64 participants | Very low |