Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Benzodiazepines (lorazepam) vs diazepam

Additional drugs required to stop the seizure: additional dose of the trial drug required · Children with acute tonic‐clonic seizures

Summary of findings ‐ Lorazepam showed no clear difference in additional drugs required to terminate the seizure: additional dose… compared with diazepam (low certainty).

1 finding from 1 review