Treatment discontinuation · participants with hidradenitis suppurativa
Adalimumab every other week showed no clear difference in frequency of treatment discontinuation compared with placebo (high certainty).
1 finding from 1 review
Proportion of participants with infectious adverse effects · participants with hidradenitis suppurativa
Adalimumab every other week showed no clear difference in proportion of participants with infectious adverse effects compared with placebo (high certainty).
1 finding from 1 review
Change in Pain VAS · participants with hidradenitis suppurativa
1 finding from 1 review
Proportion with improvement in pain · participants with hidradenitis suppurativa
Adalimumab every other week showed no clear difference in proportion with improvement in pain compared with placebo (moderate certainty).
1 finding from 1 review
Change in Sartorius scale score (LOCF) · participants with hidradenitis suppurativa
1 finding from 1 review
At least 50% decrease in HS Severity Index · participants with hidradenitis suppurativa
Infliximab showed no clear difference in at least 50% decrease in HS Severity Index compared with placebo (moderate certainty).
1 finding from 1 review
Physician Global Assessment (Thongprasom score) · participants with hidradenitis suppurativa
Infliximab probably leads to higher physician global assessment compared with placebo (moderate certainty).
1 finding from 1 review
Secondary outcome: Dermatology Quality of Life measure · participants with hidradenitis suppurativa
1 finding from 1 review
Adverse effects (non‐serious) · participants with hidradenitis suppurativa
Topical clindamycin showed no clear difference in adverse effects (non‐serious) compared with placebo (moderate certainty).
1 finding from 1 review
Frequency of serious adverse effects · participants with hidradenitis suppurativa
Adalimumab weekly showed no clear difference in frequency of serious adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Treatment discontinuation · participants with hidradenitis suppurativa
Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).
1 finding from 1 review
Physician Global Assessment (Thongprasom score) · participants with hidradenitis suppurativa
Staphage lysate probably leads to higher physician global assessment compared with placebo broth (moderate certainty).
1 finding from 1 review
Proportion of participants with infectious adverse effects · participants with hidradenitis suppurativa
Adalimumab weekly showed no clear difference in proportion of participants with infectious adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Proportion with improvement in pain VAS · participants with hidradenitis suppurativa
Adalimumab weekly probably leads to higher proportion with improvement in pain VAS compared with placebo (moderate certainty).
1 finding from 1 review
Change in modified Sartorius scale score (imputation) · participants with hidradenitis suppurativa
1 finding from 1 review
Change in DLQI score (LOCF) · participants with hidradenitis suppurativa
1 finding from 1 review
Frequency of serious adverse effects · participants with hidradenitis suppurativa
Adalimumab every other week showed no clear difference in frequency of serious adverse effects compared with placebo (high certainty).
1 finding from 1 review
Incidence of herpes labialis after use of the preventative intervention · participants with recurrent herpes labialis
Oral aciclovir (short‐term) showed no clear difference in incidence of herpes labialis during use of the preventative… compared with placebo (moderate certainty).
1 finding from 1 review
Adherence · participants with recurrent herpes labialis
1 finding from 1 review
Incidence of herpes labialis after use of the preventative intervention · participants with recurrent herpes labialis
Valaciclovir (short‐term) showed no clear difference in incidence of HSL during use of the preventative intervention (by… compared with placebo (moderate certainty).
1 finding from 1 review