Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,536 questions · 2,637 findings · 315 reviews

No studies found 608 · 23.1%GRADE not reported 488 · 18.5%Very low 688 · 26.1%Low 540 · 20.5%Moderate 249 · 9.4%High 64 · 2.4%

Povidone iodine coolant vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): cinnamon extract coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether povidone iodine coolant changes reduction in level of contamination in aerosols (CFU): povidone… compared with distilled water coolant (very low certainty).

1 finding from 1 review

Interventions for involving older patients with multi‐morbidity in decision‐making about their health care vs usual care

Practitioners' knowledge and skills Not measured · older patients with multi‐morbidity

The review found no eligible studies for this question.

1 finding from 1 review

Telephone quitline referral vs usual care or no treatment

Health system telephone counselling vs quitline · smoking cessation in hospitalised patients

It is very uncertain whether telephone quitline referral changes health system telephone counselling vs quitline compared with no treatment or usual care (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes non‐surgical therapy for recurrent or persistent diseaseRadiation… compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes implant failure rate compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes need for additional augmentation prior to implant placement compared with extraction alone (very low certainty).

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) showed no clear difference in bone gain (horizontal - HDD) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) showed no clear difference in bone gain (vertical - VDH) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review