Disease or progression‐free survival Median · women with locally advanced cervical cancer
Hysterectomy (simple or radical) with neoadjuvant chemotherapy showed no clear difference in disease‐ or progression‐free survival Median compared with radiotherapy alone (moderate certainty).
1 finding from 1 review
Quality of life · women with locally advanced cervical cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severe adverse events and toxicity · women with locally advanced cervical cancer
Hysterectomy (simple or radical) with neoadjuvant chemotherapy showed no clear difference in severe adverse events and toxicity compared with radiotherapy alone (low certainty).
1 finding from 1 review
Supportive periodontal therapy (SPT) including mechanical debridement vs Monitoring only, or alternative interventions that do not include mechanical debridement
Outcome not reported · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Frequent relapses · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in number with frequent relapses by 12 to 24 months compared with 2 months of therapy (moderate certainty).
1 finding from 1 review
Number of children relapsing by 12 to 24 months · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… may leads to lower number of children relapsing by 12 to 24 months compared with 2 months of therapy (low certainty).
1 finding from 1 review
Number with frequent relapses by 12 to 24 months stratified by risk of selection bias: Low risk of selection bias · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in number with frequent relapses by 12 to 24 months stratified by risk… compared with 2 months of therapy (high certainty).
1 finding from 1 review
Number with frequent relapses by 12 to 24 months stratified by risk of bias for allocation concealment: unclear or high risk of bias for allocation bias · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… may leads to lower number with frequent relapses by 12 to 24 months stratified by risk… compared with 2 months of therapy (low certainty).
1 finding from 1 review
Adverse events: psychological disorders · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: psychological disorders compared with 2 months of therapy (low certainty).
1 finding from 1 review
Adverse events: hypertension · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: hypertension compared with 2 months of therapy (moderate certainty).
1 finding from 1 review
Adverse events: Cushing's syndrome · children with nephrotic syndrome
Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: Cushing's syndrome compared with 2 months of therapy (moderate certainty).
1 finding from 1 review
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review
Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Pruritus · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
QoL · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Adverse events · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Adherence · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Quality of life · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
The review found no eligible studies for this question.
1 finding from 1 review
Overall survival, induction cisplatin + 5-fluorouracil + docetaxel prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction cisplatin + 5-fluorouracil + docetaxel… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower locoregional control, induction cisplatin + 5-fluorouracil +… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
RR 0.80 [0.64, 0.99]
3 studies
GRADE not reported