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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

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No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Side effects: gastrointestinal disturbances (diarrhoea, lower abdominal pain), headache and sweating

It is very uncertain whether interventions (vitamin B1, mefenamic acid, tranexamic acid) changes side effects: gastrointestinal disturbances (diarrhoea, lower… compared with placebo or active comparators (desmopressin, sodium diclofenac,… (very low certainty).

1 finding from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Menstrual blood loss PBAC score
2 findings from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Menstrual blood loss Number of pads (diary record)
2 findings from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Duration of bleeding Number of bleeding days
2 findings from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Adverse effects: headache

Interventions (vitamin B1, mefenamic acid, tranexamic acid) showed no clear difference in side effects: headache compared with placebo or active comparators (desmopressin, sodium diclofenac,… (low certainty).

1 finding from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Vomiting

Interventions (vitamin B1, mefenamic acid, tranexamic acid) showed no clear difference in side effects: vomiting compared with placebo or active comparators (desmopressin, sodium diclofenac,… (low certainty).

1 finding from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Duration of bleeding (menstrual diary)
2 findings from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Menstrual blood loss: mean loss
2 findings from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Prevalence of adults with probable PTSD (1 to 6 months post intervention) Diagnosis defined by HTQ ≥ 1.75 (RR > 1 denotes lower prevalence compared to control) · adults with post‐traumatic stress or common mental disorders

Primary health professional‐led psychological interventions may leads to higher prevalence of adults with probable PTSD (1 to 6 months post… compared with usual or no care (low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Anxiety and depression · adults with post‐traumatic stress or common mental disorders

Primary health professional‐led psychological interventions may leads to higher prevalence of adults with probable depression or anxiety (1 to 6… compared with usual or no care (low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Severity of PTSD symptoms · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes PTS symptoms (1 to 6 months post intervention) Harvard Trauma… compared with usual or no care (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Depression symptoms (1 to 6 months post intervention) Hopkins Symptom Checklist ‐ depression (higher score = higher severity) · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes depression symptoms (1 to 6 months post intervention) Hopkins… compared with usual or no care (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Functional impairment · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes functional impairment (1 to 6 months post intervention) Locally… compared with usual or no care (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Adverse events (RR > 1 denotes greater risk of harm) · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes adverse events (RR > 1 denotes greater risk of harm) compared with usual or no care (very low certainty).

1 finding from 1 review