Findings

What do systematic reviews say?

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

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No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Augmented supported employment vs. psychiatric care only · adults with severe mental illness

The intervention probably leads to higher augmented supported employment vs. psychiatric care only (moderate certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 3.81 [1.99, 7.31]
1 study · 256 participants
Moderate

Intervention not reported

Augmented supported employment vs supported employment only · adults with severe mental illness

The intervention showed no clear difference in augmented supported employment vs supported employment only (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 1.4 [0.92, 2.14]
3 studies · 205 participants
Low

Intervention not reported

Supported employment vs. psychiatric care only · adults with severe mental illness

The intervention may leads to higher supported employment vs. psychiatric care only (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 2.72 [1.55, 4.76]
1 study · 2238 participants
Low

Intervention not reported

Pre‐vocational training vs. psychiatric care only · adults with severe mental illness

It is very uncertain whether the intervention changes pre‐vocational training vs. psychiatric care only (very low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 1.26 [0.73, 2.19]
2 studies · 161 participants
Very low

Intervention not reported

Transitional employment vs. psychiatric care only · adults with severe mental illness

The intervention showed no clear difference in transitional employment vs. psychiatric care only (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 1 [0.51, 1.96]
0 participants
Low

Intervention not reported

Augmented supported employment vs. transitional employment · adults with severe mental illness

The intervention may leads to higher augmented supported employment vs. transitional employment (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 3.79 [2.34, 6.14]
2 studies · 212 participants
Low

Intervention not reported

Supported employment vs. transitional employment · adults with severe mental illness

The intervention probably leads to higher supported employment vs. transitional employment (moderate certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 2.71 [1.8, 4.06]
4 studies · 87 participants
Moderate

Intervention not reported

Pre‐vocational training vs. transitional employment · adults with severe mental illness

The intervention showed no clear difference in pre‐vocational training vs. transitional employment (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 1.26 [0.77, 2.05]
0 participants
Low

Intervention not reported

Augmented supported employment vs. pre‐vocational training · adults with severe mental illness

The intervention may leads to higher augmented supported employment vs. pre‐vocational training (low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 3.02 [1.88, 4.87]
2 studies · 193 participants
Low

Intervention not reported

Supported employment vs prevocational training · adults with severe mental illness

It is very uncertain whether the intervention changes supported employment vs prevocational training (very low certainty).

1 finding from 1 review

Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta‐analysis 2017 · Cochrane Headline outcomes only
RR 2.16 [1.59, 2.93]
9 studies · 1569 participants
Very low

Remifentanil (PCA) vs another opioid (IV/IM)

Satisfaction with pain relief · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 216 participants
Very low

Remifentanil (PCA) vs another opioid (PCA)

Additional analgesia required (escape analgesia) · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in additional analgesia required (escape analgesia) compared with another opioid (PCA) (low certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 0.76 [0.45, 1.28]
3 studies · 215 participants
Low

Remifentanil (PCA) vs another opioid (PCA)

Caesarean section · women in labour with planned vaginal delivery

It is very uncertain whether remifentanil (PCA) changes rate of caesarean delivery compared with another opioid (PCA) (very low certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 2.78 [0.99, 7.82]
2 studies · 143 participants
Very low

Remifentanil (PCA) vs another opioid (PCA)

Maternal apnoea · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Remifentanil (PCA) vs another opioid (PCA)

Maternal respiratory depression (< 8 breaths/min) · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Remifentanil (PCA) vs another opioid (PCA)

Low Apgar score · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Remifentanil (PCA) vs epidural/CSE

Satisfaction with pain relief · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2135 participants
Very low

Remifentanil (PCA) vs epidural/CSE

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 235 participants
Low

Remifentanil (PCA) vs epidural/CSE

Additional analgesia required (escape analgesia) · women in labour with planned vaginal delivery

Remifentanil (PCA) probably leads to higher additional analgesia required compared with epidural/CSE (moderate certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 9.27 [3.73, 23.03]
6 studies · 1037 participants
Moderate

Remifentanil (PCA) vs epidural/CSE

Caesarean section · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in rate of caesarean delivery compared with epidural/CSE (moderate certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 1 [0.82, 1.22]
9 studies · 1578 participants
Moderate