Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Acceptability · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).

2 findings from 1 review

Psychological interventions vs treatment

Acceptability · adults with long‐term physical conditions (18 years or older)

Psychological interventions may leads to higher acceptability ‐ drop‐outs due to any cause: post‐intervention compared with treatment (low certainty).

2 findings from 1 review

Intervention not reported

Clinical malaria · children under 12 months of age

The intervention probably leads to lower clinical malaria (moderate certainty).

1 finding from 1 review

Intervention not reported

Hospital admission for any reason · malaria in infants

The intervention showed no clear difference in hospital admission for any reason (moderate certainty).

1 finding from 1 review

Intervention not reported

Parasitaemia · malaria in infants

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Anaemia · malaria in infants

The intervention showed no clear difference in anaemia (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical malaria · malaria in infants

The intervention probably leads to lower clinical malaria (moderate certainty).

1 finding from 1 review

Intervention not reported

Severe malaria · malaria in infants

The intervention showed no clear difference in severe malaria (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality · malaria in infants

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review