Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,695 questions · 4,979 findings · 433 reviews

No studies found 998 · 20%GRADE not reported 1,140 · 22.9%Very low 1,024 · 20.6%Low 1,029 · 20.7%Moderate 636 · 12.8%High 152 · 3.1%

ORS ≤ 270 mOsm/L (rice‐based) vs ORS ≥ 310 mOsm/L (glucose‐based)

Severe biochemical hyponatraemia (serum sodium < 125 mmol/L) · patients with cholera

ORS ≤ 270 mOsm/L (rice‐based) showed no clear difference in severe biochemical hyponatraemia(serum sodium < 125 mmol/L) compared with ORS ≥ 310 mOsm/L (glucose‐based) (low certainty).

1 finding from 1 review

ORS ≤ 270 mOsm/L (rice‐based) vs ORS ≥ 310 mOsm/L (glucose‐based)

Hyponatraemia (< 130 mmol/L) · patients with cholera

ORS ≤ 270 mOsm/L (rice‐based) showed no clear difference in biochemical hyponatraemia(serum sodium < 130 mmol/L) compared with ORS ≥ 310 mOsm/L (glucose‐based) (low certainty).

1 finding from 1 review

ORS ≤ 270 mOsm/L (glucose‐based) vs ORS ≥ 310 mOsm/L (glucose‐based)

Need for unscheduled intravenous infusion · patients with cholera

ORS ≤ 270 mOsm/L (glucose‐based) showed no clear difference in need for unscheduled intravenous infusion compared with ORS ≥ 310 mOsm/L (glucose‐based) (moderate certainty).

1 finding from 1 review

ORS ≤ 270 mOsm/L (glucose‐based) vs ORS ≥ 310 mOsm/L (glucose‐based)

Hyponatraemia (< 130 mmol/L) · patients with cholera

ORS ≤ 270 mOsm/L (glucose‐based) probably leads to higher biochemical hyponatraemia (serum sodium < 130 mmol/L) compared with ORS ≥ 310 mOsm/L (glucose‐based) (moderate certainty).

1 finding from 1 review

ORS ≤ 270 mOsm/L (glucose‐based) vs ORS ≥ 310 mOsm/L (glucose‐based)

Severe biochemical hyponatraemia (serum sodium < 125 mmol/L) · patients with cholera

ORS ≤ 270 mOsm/L (glucose‐based) showed no clear difference in severe biochemical hyponatraemia (serum sodium < 125 mmol/L) compared with ORS ≥ 310 mOsm/L (glucose‐based) (low certainty).

1 finding from 1 review