Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Rotarix vs placebo

Severe cases of rotavirus diarrhoea · children

Rotarix leads to lower severe cases of rotavirus diarrhoea compared with placebo (high certainty).

6 findings from 1 review
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Rotarix vs placebo

Severe cases of all‐cause diarrhoea · children

Rotarix leads to lower severe cases of all‐cause diarrhoea compared with placebo (high certainty).

6 findings from 1 review
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Rotarix vs placebo

All‐cause death · children

Rotarix showed no clear difference in all‐cause death compared with placebo (moderate certainty).

3 findings from 1 review

Rotarix vs placebo

All serious adverse events · children

Rotarix leads to lower all serious adverse events compared with placebo (high certainty).

3 findings from 1 review

Rotarix vs placebo

Serious adverse events: intussusception · children

Rotarix showed no clear difference in serious adverse events: intussusception compared with placebo (low certainty).

3 findings from 1 review

RotaTeq vs placebo

Severe cases of rotavirus diarrhoea · children

RotaTeq leads to lower severe cases of rotavirus diarrhoea compared with placebo (high certainty).

6 findings from 1 review
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RotaTeq vs placebo

Severe cases of all‐cause diarrhoea · children

The review found no eligible studies for this question.

6 findings from 1 review
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RotaTeq vs placebo

All‐cause death · children

RotaTeq showed no clear difference in all‐cause death compared with placebo (low certainty).

3 findings from 1 review

RotaTeq vs placebo

All serious adverse events · children

RotaTeq showed no clear difference in all serious adverse events compared with placebo (high certainty).

3 findings from 1 review

RotaTeq vs placebo

Serious adverse events: intussusception · children

RotaTeq showed no clear difference in serious adverse events: intussusception compared with placebo (low certainty).

3 findings from 1 review

Rotasiil vs placebo

Severe cases of all‐cause diarrhoea · children

Rotasiil showed no clear difference in severe cases of all‐cause diarrhoea compared with placebo (high certainty).

2 findings from 1 review

Rotavac vs placebo

Severe cases of rotavirus diarrhoea · children

Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty).

2 findings from 1 review