Tooth staining/discolouration (adverse effect) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…
Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in adverse effects (tooth staining, Meckel Stain Score, 6 months) compared with fluoride toothpaste without triclosan; GRADE not reported.
There was no evidence to support the use of adjunctive technologies like toluidine blue, brush biopsy or fluorescence imaging as a screening tool to reduce oral cancer mortality; no eligible randomised controlled trial…