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Evidence found and GRADE certainty

550 questions · 581 findings · 23 reviews · Implants and prosthodontics

No studies found 87 · 15%GRADE not reported 388 · 66.8%Very low 88 · 15.1%Low 10 · 1.7%Moderate 8 · 1.4%High 0 · 0%

Phosphoric etching (acid) gel vs Mechanical debridement and polishing

Change in probing pocket depth (PPD) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Phosphoric etching (acid) gel showed no clear difference in change in probing pocket depth compared with mechanical debridement and polishing; GRADE not reported.

1 finding from 1 review

Immediate implants (placed in a fresh extraction socket just after tooth extraction) vs Delayed implants (placed at least 2 months after extraction)

Aesthetics assessed by dentist: position of the perimplant tissues · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate implants (placed in a fresh extraction socket just after… led to lower aesthetics assessed by dentist: position of the perimplant tissues compared with delayed implants (placed at least 2 months after extraction, in…; GRADE not reported.

1 finding from 1 review

Triclosan dentifrice vs Sodium fluoride (control) toothpaste

Change in probing pocket depth (>=4 mm) · Adults with dental implants and peri-implant mucositis at baseline

Triclosan dentifrice showed no clear difference in change in probing pocket depth (>=4 mm) compared with sodium fluoride dentifrice; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Non-resorbable barrier (guided bone regeneration)

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.

1 finding from 1 review

Immediate-delayed implants (placed within 8 weeks after tooth extraction) vs Delayed implants (placed at least 2 months after extraction)

Prosthesis failure · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate-delayed implants (placed within 8 weeks after tooth… led to lower prosthesis failure compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site led to lower major complications at the implant/donor site compared with no augmentation; GRADE not reported.

1 finding from 1 review

Immediate implants (placed in a fresh extraction socket just after tooth extraction) vs Immediate-delayed implants (placed within 8 weeks after tooth extraction)

Marginal bone level change · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate implants (placed just after tooth extraction) showed no clear difference in perimplant marginal bone level changes compared with immediate-delayed implants (placed within 8 weeks after tooth…; GRADE not reported.

1 finding from 1 review

Immediate implants (placed in a fresh extraction socket just after tooth extraction) vs Delayed implants (placed at least 2 months after extraction)

Implant failure · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate implants (placed in a fresh extraction socket just after… showed no clear difference in implant failure compared with delayed implants (placed at least 2 months after extraction, in…; GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (vertical - VDH) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Immediate-delayed implants (placed within 8 weeks after tooth extraction) vs Delayed implants (placed at least 2 months after extraction)

Satisfaction with treatment ‐ general · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate-delayed implants (placed within 8 weeks after tooth… led to higher patients' general satisfaction of treatment compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Poor aesthetics measured by patient (after restoration) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by patient (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash

Patient satisfaction (desire for future use) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash led to higher patient satisfaction (desire for future use) compared with chlorhexidine mouthwash; GRADE not reported.

1 finding from 1 review

Immediate-delayed implants (placed within 8 weeks after tooth extraction) vs Delayed implants (placed at least 2 months after extraction)

Patients' perception of how long treatment took · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets

Immediate-delayed implants (placed within 8 weeks after tooth… led to lower patients' perception of how long treatment took compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.

1 finding from 1 review

Mechanical debridement plus topical minocycline vs Mechanical debridement plus chlorhexidine gel

Change in probing pocket depth (worst sites) · Adults with dental implants and peri-implant mucositis at baseline

Mechanical debridement plus topical minocycline showed no clear difference in change in probing pocket depth (worst sites) compared with mechanical debridement plus chlorhexidine gel; GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (horizontal - HDD) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Change in probing pocket depth (PPD) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in change in probing pocket depth compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review