Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D4: Survival free of major neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D4: Survival free of major neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Maternal death · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B1: Maternal death – all women compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

B2: Maternal sepsis – an all women · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B2: Maternal sepsis – an all women compared with single course (moderate certainty).

1 finding from 1 review

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Women not using/receiving misoprostol at birth · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes women not using/receiving misoprostol at birth compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Inappropriate use (or misuse) of misoprostol · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes inappropriate use (or misuse) of misoprostol compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Maternal transfer or referral to a health facility · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes maternal transfer or referral to a health facility compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Intervention not reported

Lower limb compression vs control · women having spinal anaesthesia for caesarean section

It is very uncertain whether the intervention changes lower limb compression vs control (very low certainty).

1 finding from 1 review