Laxation response: patient assessment of change in bowel status at the end of trial · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction
Methylnaltrexone lower dose showed no clear difference in laxation response: patient assessment of change in bowel statusgat… compared with higher dose (low certainty).
1 finding from 1 review
Symptoms of opioid withdrawal in the medium term · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction
Methylnaltrexone lower dose showed no clear difference in symptoms of opioid withdrawal in the medium term compared with higher dose (low certainty).
1 finding from 1 review
Serious adverse events · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction
Methylnaltrexone lower dose showed no clear difference in adverse events compared with higher dose (low certainty).
1 finding from 1 review
Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Intralesional betamethasone may leads to higher clinical resolution compared with intralesional triamcinolone acetonide (low certainty).
1 finding from 1 review
Clinical score (14 days) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
It is very uncertain whether intralesional betamethasone changes clinical score (14 days) compared with intralesional triamcinolone acetonide (very low certainty).
1 finding from 1 review
Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
It is very uncertain whether systemic (oral) betamethasone changes clinical score compared with topical triamcinolone acetonide paste (very low certainty).
1 finding from 1 review
Pain / clinical response (not analysable) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
1 finding from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD -0.47 [-0.68, -0.26]
6 studies · 215 participants
GRADE not reported
MD -0.18 [-0.33, -0.04]
15 studies · 562 participants
GRADE not reported
MD -0.30 [-0.42, -0.18]
2 studies · 389 participants
Very low
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)
Amoxicillin + metronidazole + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether amoxicillin + metronidazole + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
2 findings from 1 review
Adverse events · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in adverse events compared with clarithromycin + SRP; GRADE not reported.
1 finding from 1 review
Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)
Amoxicillin + metronidazole + SRP led to lower percentage of closed pockets compared with SRP; GRADE not reported.
2 findings from 1 review
MD -13.90 [-24.16, -3.64]
1 study · 44 participants
GRADE not reported
MD -16.20 [-25.87, -6.53]
1 study · 44 participants
Very low
Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in percentage of bleeding on probing (BOP) compared with clarithromycin + SRP; GRADE not reported.
1 finding from 1 review
Antimicrobial resistance · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Ulcer healing · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of wounds healed · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found