Intervention not reported
Intelligence Measured by: standardized IQ tests (mean = 100 (SD = 15); higher scores indicate higher IQ) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Problem behavior Measured by: standardized parent‐report measures and checklists (lower scores indicate lower levels or less severe problem behavior) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Duration of mechanical ventilation · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
ICU mortality · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in ICU mortality compared with usual care (low certainty).
1 finding from 1 review
Hospital mortality · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in hospital mortality compared with usual care (low certainty).
1 finding from 1 review
Duration of ICU stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Length of hospital stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Adverse event ‐ incidence of self‐extubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of self‐extubation (in ICU) compared with usual care (high certainty).
1 finding from 1 review
Adverse event ‐ incidence of reintubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of reintubation (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Incidence of tracheostomy (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in incidence of tracheostomy (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Ventilator‐free days (within the first 30 days) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Duration of ICU stay · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
It is very uncertain whether physical and cognitive therapy changes length of ICU stay (days) compared with standard care (very low certainty).
1 finding from 1 review
Cognitive function · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Cognitive functioning b) Executve functioning (DEX score) (scores range from 0 to 80. Lower scores indicate better functioning) (DEX) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Adverse events · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
In‐hospital mortality within 28 days. · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
Haloperidol showed no clear difference in in‐hospital mortality within 28 days. compared with placebo (moderate certainty).
1 finding from 1 review
Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
1 finding from 1 review