Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

679 questions · 687 findings · 43 reviews

No studies found 169 · 24.6%GRADE not reported 172 · 25%Very low 157 · 22.9%Low 128 · 18.6%Moderate 47 · 6.8%High 14 · 2%

PLMA vs tracheal tube

Laryngospasm/bronchoconstriction between induction and recovery · airway management during general anaesthesia in obese participants

It is very uncertain whether PLMA changes laryngospasm/bronchoconstriction between induction and recovery compared with tracheal tube (very low certainty).

1 finding from 1 review

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section

Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with high‐dose spinal (low certainty).

1 finding from 1 review

Combined spinal‐epidural vs low‐dose spinal

Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section

Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with low‐dose spinal (low certainty).

1 finding from 1 review

Neuraxial vs general anaesthesia

Return of patient to their own home · Patients with hip fracture repair

It is very uncertain whether neuraxial block changes return of patient to their own home compared with general anaesthesia (very low certainty).

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Postoperative mortality · adult participants given general anaesthesia

It is very uncertain whether PEEP changes postoperative mortality compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Pneumonia · adult participants given general anaesthesia

It is very uncertain whether PEEP changes pneumonia compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review