Findings

What do systematic reviews say?

4,695 questions · 4,979 findings · 433 reviews

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No studies found 998 · 20%GRADE not reported 1,140 · 22.9%Very low 1,024 · 20.6%Low 1,029 · 20.7%Moderate 636 · 12.8%High 152 · 3.1%

Intervention not reported

Hb (g/L) ‐ before further donation Scale from: 123 to 152 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 847 participants
Moderate

Intervention not reported

Hb (g/L) ‐ after subsequent donation(s) Scale from: 127.3 to 129 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 406 participants
Moderate

Intervention not reported

Serum ferritin (ng/mL) ‐ before further donation Scale from: 12.9 to 57.8 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 640 participants
Moderate

Intervention not reported

Serum ferritin (ng/mL) ‐ after subsequent donation(s) Scale from: 18 to 19 · patients with iron deficiency and/or anaemia in blood donors

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 619 participants
Moderate

Intervention not reported

Adverse effects (any) · patients with iron deficiency and/or anaemia in blood donors

The intervention probably leads to higher adverse effects (any) (moderate certainty).

1 finding from 1 review

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors 2014 · Cochrane Headline outcomes only
RR 1.6 [1.23, 2.07]
4 studies · 1748 participants
Moderate

FNB (any type) vs another opioid (PCA)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1066 participants
Moderate

FNB (any type) vs epidural analgesia

Neurological injury · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 306 participants
GRADE not reported

FNB (any type) vs epidural analgesia

Opioid consumption at 24 hours using morphine equivalents Scale from zero to 150 mg · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 341 participants
High

FNB (any type) vs epidural analgesia

Maternal nausea and/or vomiting · patients with knee replacement surgery

FNB (any type) probably leads to lower nausea and/or vomiting compared with epidural analgesia (moderate certainty).

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
RR 0.63 [0.41, 0.97]
4 studies · 183 participants
Moderate

FNB (any type) vs epidural analgesia

Knee flexion range of motion (degree) · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 328 participants
High

FNB (any type) vs epidural analgesia

Participant satisfaction with analgesia (point) Scale from zero to 10 · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
Low

FNB (any type) vs local infiltration analgesia

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 216 participants
Moderate

FNB (any type) vs local infiltration analgesia

Pain on movement at 24 hours Visual analogue scale Scale from zero to 10 · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 153 participants
Low

FNB (any type) vs local infiltration analgesia

Neurological injury: not reported · patients with knee replacement surgery

The review found no eligible studies for this question.

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

FNB (any type) vs local infiltration analgesia

Opioid consumption at 24 hours using morphine equivalents Scale from zero to 150 mg · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Moderate

FNB (any type) vs local infiltration analgesia

Maternal nausea and/or vomiting · patients with knee replacement surgery

FNB (any type) showed no clear difference in nausea and/or vomiting compared with local infiltration analgesia (moderate certainty).

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
RR 1.71 [0.64, 4.62]
3 studies · 177 participants
Moderate

FNB (any type) vs another opioid (PCA)

Pain on movement at 24 hours Visual analogue scale Scale from zero to 10 · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 1017 participants
Moderate

FNB (any type) vs local infiltration analgesia

Participant satisfaction with analgesia (point) Scale from zero to 10 · patients with knee replacement surgery

The review found no eligible studies for this question.

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous FNB vs single‐shot FNB

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 272 participants
Moderate

Continuous FNB vs single‐shot FNB

Pain on movement at 24 hours Visual analogue scale Scale from zero to 10 · patients with knee replacement surgery

1 finding from 1 review

Femoral nerve blocks for acute postoperative pain after knee replacement surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 272 participants
High