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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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UVA1 vs narrowband UVB

Proportion of participants with adverse effects serious or severe enough to have caused withdrawal ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

UVA1 vs narrowband UVB

Proportion of participants with at least 50% improvement in their quality of life ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

UVA1 vs narrowband UVB

Proportion of participants achieving a 50% reduction in disease severity ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

UVA1 vs narrowband UVB

Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants cleared or almost cleared in the short… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants without relapse in the long term (6 months) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants with adverse effects ‐ measured over 12… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate with PUVA therapy as co‐intervention vs placebo with PUVA therapy

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether etretinate with PUVA therapy as co‐intervention changes proportion of participants cleared or almost cleared in the short… compared with placebo with PUVA therapy (very low certainty).

1 finding from 1 review