Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Magnesium sulphate vs hypertonic saline

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with hypertonic saline (very low certainty).

1 finding from 1 review

Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol

Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured at 0 to 24 hoursafter treatment · children from 1 month to 24 months old with acute bronchiolitis

The review found no eligible studies for this question.

1 finding from 1 review

Magnesium sulphate or magnesium sulphate + salbutamol vs salbutamol

Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured 25 to 48 hoursafter treatment · children from 1 month to 24 months old with acute bronchiolitis

The review found no eligible studies for this question.

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Length of hospital stay · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes duration of hospital stay compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured at 0 to 24 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo

Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured at 0 to 24 hoursafter treatment · children up to 18 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (Wang score; range 0 to 12; higher =… compared with placebo (very low certainty).

1 finding from 1 review