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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Stunting · children under 5 years old

Micronutrient or macronutrient supplementation interventions in… showed no clear difference in height‐for‐age (z‐score) compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (low certainty).

1 finding from 1 review

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Height‐for‐age (z‐score) Length gain (6 months) · children under 5 years old
1 finding from 1 review

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Height‐for‐age (%) at 18 months, 21 months Length gain · children under 5 years old
1 finding from 1 review

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Length velocity (change in cm since start of supplementation) · children under 5 years old
1 finding from 1 review

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Length velocity (cm/month) · children under 5 years old

It is very uncertain whether micronutrient or macronutrient supplementation interventions in… changes length velocity (cm/month) compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (very low certainty).

1 finding from 1 review

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Length (cm) · children under 5 years old

Micronutrient or macronutrient supplementation interventions in… showed no clear difference in length (cm) at 12 months compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (low certainty).

1 finding from 1 review

NSAIDs vs control or placebo medications

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Nonsteroidal anti‐inflammatory drugs (NSAIDs) showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).

1 finding from 1 review