Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Intervention not reported

Clinical score of dryness Hahnel 2017: measured at day 56 ± 4 using the Overall Dry Skin Score Boccanfuso 1978: measured after 10 applications using a non‐validated General Foot Condition Questionnaire including a Dryness Scale (1 = oily; 2 = norm... · people 60 years of age and older
1 finding from 1 review

Oral nutritional supplements vs placebo

Ulcer healing · people with diabetes and foot ulcers

The review found no eligible studies for this question.

2 findings from 1 review

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

Development of any new foot ulcers · people with diabetes and foot ulcers

It is very uncertain whether arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement changes development of any new foot ulcers compared with placebo (very low certainty).

1 finding from 1 review

220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo

Ulcer healing · people with diabetes and foot ulcers

It is very uncertain whether 220 mg zinc sulphate supplement containing 50 mg elemental zinc changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).

4 findings from 1 review
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250 mg magnesium oxide supplement vs placebo

Ulcer healing · people with diabetes and foot ulcers

It is very uncertain whether 250 mg magnesium oxide supplement changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).

4 findings from 1 review
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1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo

Ulcer healing · people with diabetes and foot ulcers

It is very uncertain whether 1000 mg/day omega‐3 fatty acid from flaxseed oil supplement changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).

4 findings from 1 review
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